Wang GG - Search Results

1

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.

Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG. Zhang Y, et al. Among authors: wang gg. Nat Commun. 2020 Jul 3;11(1):3339. doi: 10.1038/s41467-020-17098-4. Nat Commun. 2020. PMID: 32620764 Free PMC article.

2

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.

Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD. Wang GG, et al. Among authors: wang z. Nature. 2009 Jun 11;459(7248):847-51. doi: 10.1038/nature08036. Nature. 2009. PMID: 19430464 Free PMC article.

3

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.

Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. Cai L, et al. Among authors: wang gg. Mol Cell. 2013 Feb 7;49(3):571-82. doi: 10.1016/j.molcel.2012.11.026. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273982 Free PMC article.

4

NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.

Gough SM, Lee F, Yang F, Walker RL, Zhu YJ, Pineda M, Onozawa M, Chung YJ, Bilke S, Wagner EK, Denu JM, Ning Y, Xu B, Wang GG, Meltzer PS, Aplan PD. Gough SM, et al. Among authors: wang gg. Cancer Discov. 2014 May;4(5):564-77. doi: 10.1158/2159-8290.CD-13-0419. Epub 2014 Feb 17. Cancer Discov. 2014. PMID: 24535671 Free PMC article.

5

Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia.

Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, Zheng D, Jin J, Wang GG. Xu B, et al. Among authors: wang gg. Blood. 2015 Jan 8;125(2):346-57. doi: 10.1182/blood-2014-06-581082. Epub 2014 Nov 13. Blood. 2015. PMID: 25395428 Free PMC article.

6

The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.

Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG. Xu B, et al. Among authors: wang gg. Stem Cell Reports. 2018 Mar 13;10(3):675-683. doi: 10.1016/j.stemcr.2018.01.020. Epub 2018 Feb 15. Stem Cell Reports. 2018. PMID: 29456179 Free PMC article.

7

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer.

Cai L, Tsai YH, Wang P, Wang J, Li D, Fan H, Zhao Y, Bareja R, Lu R, Wilson EM, Sboner A, Whang YE, Zheng D, Parker JS, Earp HS, Wang GG. Cai L, et al. Among authors: wang gg, wang j, wang p. Mol Cell. 2018 Oct 18;72(2):341-354.e6. doi: 10.1016/j.molcel.2018.08.029. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270106 Free PMC article.

8

A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3A^R882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis.

Lu R, Wang J, Ren Z, Yin J, Wang Y, Cai L, Wang GG. Lu R, et al. Among authors: wang gg, wang j, wang y. Cancer Res. 2019 Jul 15;79(14):3583-3594. doi: 10.1158/0008-5472.CAN-18-3275. Epub 2019 Jun 4. Cancer Res. 2019. PMID: 31164355 Free PMC article.

9

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation.

Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG. Ren Z, et al. Among authors: wang gg, wang p. Blood. 2019 Oct 3;134(14):1176-1189. doi: 10.1182/blood.2019000578. Epub 2019 Aug 5. Blood. 2019. PMID: 31383640 Free PMC article.

10

Structure and regulation of ZCCHC4 in m⁶A-methylation of 28S rRNA.

Ren W, Lu J, Huang M, Gao L, Li D, Wang GG, Song J. Ren W, et al. Among authors: wang gg. Nat Commun. 2019 Nov 6;10(1):5042. doi: 10.1038/s41467-019-12923-x. Nat Commun. 2019. PMID: 31695039 Free PMC article.

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