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The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia.
Losson H, Gajulapalli SR, Lernoux M, Lee JY, Mazumder A, Gérard D, Seidel C, Hahn H, Christov C, Dicato M, Kirsch G, Han BW, Schnekenburger M, Diederich M. Losson H, et al. Among authors: seidel c. Pharmacol Res. 2020 Oct;160:105058. doi: 10.1016/j.phrs.2020.105058. Epub 2020 Jun 30. Pharmacol Res. 2020. PMID: 32619722
Histone deacetylase modulators provided by Mother Nature.
Seidel C, Schnekenburger M, Dicato M, Diederich M. Seidel C, et al. Genes Nutr. 2012 Jul;7(3):357-67. doi: 10.1007/s12263-012-0283-9. Epub 2012 Feb 12. Genes Nutr. 2012. PMID: 22328271 Free PMC article.
Chromatin-modifying agents in anti-cancer therapy.
Seidel C, Florean C, Schnekenburger M, Dicato M, Diederich M. Seidel C, et al. Biochimie. 2012 Nov;94(11):2264-79. doi: 10.1016/j.biochi.2012.05.012. Epub 2012 May 22. Biochimie. 2012. PMID: 22627380 Review.
Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
El Amrani M, Lai D, Debbab A, Aly AH, Siems K, Seidel C, Schnekenburger M, Gaigneaux A, Diederich M, Feger D, Lin W, Proksch P. El Amrani M, et al. Among authors: seidel c. J Nat Prod. 2014 Jan 24;77(1):49-56. doi: 10.1021/np4005745. Epub 2013 Dec 16. J Nat Prod. 2014. PMID: 24328302
Histone deacetylase 6 in health and disease.
Seidel C, Schnekenburger M, Dicato M, Diederich M. Seidel C, et al. Epigenomics. 2015;7(1):103-18. doi: 10.2217/epi.14.69. Epigenomics. 2015. PMID: 25687470 Review.
Short- and long-term gene expression profiles induced by inhaled TiO2 nanostructured aerosol in rat lung.
Chézeau L, Sébillaud S, Safar R, Seidel C, Dembélé D, Lorcin M, Langlais C, Grossmann S, Nunge H, Michaux S, Dubois-Pot-Schneider H, Rihn B, Joubert O, Binet S, Cosnier F, Gaté L. Chézeau L, et al. Among authors: seidel c. Toxicol Appl Pharmacol. 2018 Oct 1;356:54-64. doi: 10.1016/j.taap.2018.07.013. Epub 2018 Aug 4. Toxicol Appl Pharmacol. 2018. PMID: 30012374
617 results