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Page 1
Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab.
Chemello K, Beeské S, Trang Tran TT, Blanchard V, Villard EF, Poirier B, Le Bail JC, Dargazanli G, Ho-Van-Guimbal S, Boulay D, Bergis O, Pruniaux MP, Croyal M, Janiak P, Guillot E, Lambert G. Chemello K, et al. Among authors: pruniaux mp. JACC Basic Transl Sci. 2020 May 6;5(6):549-557. doi: 10.1016/j.jacbts.2020.03.008. eCollection 2020 Jun. JACC Basic Transl Sci. 2020. PMID: 32613143 Free PMC article.
SAR110894, a potent histamine H₃-receptor antagonist, displays procognitive effects in rodents.
Griebel G, Pichat P, Pruniaux MP, Beeské S, Lopez-Grancha M, Genet E, Terranova JP, Castro A, Sánchez JA, Black M, Varty GB, Weiner I, Arad M, Barak S, De Levie A, Guillot E. Griebel G, et al. Among authors: pruniaux mp. Pharmacol Biochem Behav. 2012 Aug;102(2):203-14. doi: 10.1016/j.pbb.2012.04.004. Epub 2012 Apr 21. Pharmacol Biochem Behav. 2012. PMID: 22542742
Synthesis and multiparametric evaluation of thiadiazoles and oxadiazoles as diacylglycerol acyltransferase type 1 inhibitors.
Mougenot P, Namane C, Fett E, Goumy F, Dadji-Faïhun R, Langot G, Monseau C, Onofri B, Pacquet F, Pascal C, Crespin O, Ben-Hassine M, Ragot JL, Van-Pham T, Philippo C, Chatelain-Egger F, Péron P, Le Bail JC, Guillot E, Chamiot-Clerc P, Chabanaud MA, Pruniaux MP, Ménegotto J, Schmidt F, Venier O, Viviani F, Nicolai E. Mougenot P, et al. Among authors: pruniaux mp. Bioorg Med Chem Lett. 2016 Jan 1;26(1):25-32. doi: 10.1016/j.bmcl.2015.11.046. Epub 2015 Nov 25. Bioorg Med Chem Lett. 2016. PMID: 26627579
Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1.
Mougenot P, Namane C, Fett E, Camy F, Dadji-Faïhun R, Langot G, Monseau C, Onofri B, Pacquet F, Pascal C, Crespin O, Ben-Hassine M, Ragot JL, Van-Pham T, Philippo C, Chatelain-Egger F, Péron P, Le Bail JC, Guillot E, Chamiot-Clerc P, Chabanaud MA, Pruniaux MP, Schmidt F, Venier O, Nicolaï E, Viviani F. Mougenot P, et al. Among authors: pruniaux mp. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2497-502. doi: 10.1016/j.bmcl.2012.02.006. Epub 2012 Feb 15. Bioorg Med Chem Lett. 2012. PMID: 22405833
Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy.
Beauverger P, Ozoux ML, Bégis G, Glénat V, Briand V, Philippo MC, Daveu C, Tavares G, Roy S, Corbier A, Briand P, Dorchies O, Bauchet AL, Nicolai E, Duclos O, Tamarelle D, Pruniaux MP, Muslin AJ, Janiak P. Beauverger P, et al. Among authors: pruniaux mp. Cardiovasc Res. 2020 Feb 1;116(2):329-338. doi: 10.1093/cvr/cvz097. Cardiovasc Res. 2020. PMID: 31038167
Synthesis, characterization, and biological assessment of the four stereoisomers of the H(3) receptor antagonist 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide.
Gao Z, Hurst WJ, Guillot E, Nagorny R, Pruniaux MP, Hendrix JA, George PG. Gao Z, et al. Among authors: pruniaux mp. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4044-7. doi: 10.1016/j.bmcl.2013.05.068. Epub 2013 May 30. Bioorg Med Chem Lett. 2013. PMID: 23769643
Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D.
Venier O, Pascal C, Braun A, Namane C, Mougenot P, Crespin O, Pacquet F, Mougenot C, Monseau C, Onofri B, Dadji-Faïhun R, Leger C, Ben-Hassine M, Van-Pham T, Ragot JL, Philippo C, Farjot G, Noah L, Maniani K, Boutarfa A, Nicolaï E, Guillot E, Pruniaux MP, Güssregen S, Engel C, Coutant AL, de Miguel B, Castro A. Venier O, et al. Among authors: pruniaux mp. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2414-21. doi: 10.1016/j.bmcl.2013.02.018. Epub 2013 Feb 22. Bioorg Med Chem Lett. 2013. PMID: 23478147
Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice.
Migrenne S, Lacombe A, Lefèvre AL, Pruniaux MP, Guillot E, Galzin AM, Magnan C. Migrenne S, et al. Among authors: pruniaux mp. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R929-35. doi: 10.1152/ajpregu.90824.2008. Epub 2009 Feb 11. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19211723 Free article.
24 results