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Regression of Atherosclerosis in ApoE-/- Mice Via Modulation of Monocyte Recruitment and Phenotype, Induced by Weekly Dosing of a Novel "Cytotopic" Anti-Thrombin Without Prolonged Anticoagulation.
Chen D, Li K, Festenstein S, Karegli J, Wilkinson H, Leonard H, Wei LL, Ma N, Xia M, Tam H, Wang JA, Xu Q, McVey JH, Smith RAG, Dorling A. Chen D, et al. J Am Heart Assoc. 2020 Jul 7;9(13):e014811. doi: 10.1161/JAHA.119.014811. Epub 2020 Jul 2. J Am Heart Assoc. 2020. PMID: 32611229 Free PMC article.
Expression of human tissue factor pathway inhibitor on vascular smooth muscle cells inhibits secretion of macrophage migration inhibitory factor and attenuates atherosclerosis in ApoE-/- mice.
Chen D, Xia M, Hayford C, Tham el-L, Semik V, Hurst S, Chen Y, Tam HH, Pan J, Wang Y, Tan X, Lan HY, Shen H, Kakkar VV, Xu Q, McVey JH, Dorling A. Chen D, et al. Among authors: chen y. Circulation. 2015 Apr 14;131(15):1350-60. doi: 10.1161/CIRCULATIONAHA.114.013423. Epub 2015 Feb 12. Circulation. 2015. PMID: 25677604
Manipulation of tissue factor-mediated basal PAR-2 signalling on macrophages determines sensitivity for IFNγ responsiveness and significantly modifies the phenotype of murine DTH.
Wilkinson H, Leonard H, Robson MG, Smith R, Tam E, McVey JH, Kirckhofer D, Chen D, Dorling A. Wilkinson H, et al. Among authors: chen d. Front Immunol. 2022 Sep 12;13:999871. doi: 10.3389/fimmu.2022.999871. eCollection 2022. Front Immunol. 2022. PMID: 36172348 Free PMC article.
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