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Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins.
Tranter D, Paatero AO, Kawaguchi S, Kazemi S, Serrill JD, Kellosalo J, Vogel WK, Richter U, Mattos DR, Wan X, Thornburg CC, Oishi S, McPhail KL, Ishmael JE, Paavilainen VO. Tranter D, et al. Among authors: wan x. ACS Chem Biol. 2020 Aug 21;15(8):2125-2136. doi: 10.1021/acschembio.0c00325. Epub 2020 Jul 20. ACS Chem Biol. 2020. PMID: 32608972 Free PMC article.
New Mandelalides Expand a Macrolide Series of Mitochondrial Inhibitors.
Nazari M, Serrill JD, Wan X, Nguyen MH, Anklin C, Gallegos DA, Smith AB 3rd, Ishmael JE, McPhail KL. Nazari M, et al. Among authors: wan x. J Med Chem. 2017 Sep 28;60(18):7850-7862. doi: 10.1021/acs.jmedchem.7b00990. Epub 2017 Sep 7. J Med Chem. 2017. PMID: 28841379 Free PMC article.
Canine osteosarcoma cells exhibit basal accumulation of multiple chaperone proteins and are sensitive to small molecule inhibitors of GRP78 and heat shock protein function.
Mattos DR, Weinman MA, Wan X, Goodall CP, Serrill JD, McPhail KL, Milovancev M, Bracha S, Ishmael JE. Mattos DR, et al. Among authors: wan x. Cell Stress Chaperones. 2022 May;27(3):223-239. doi: 10.1007/s12192-022-01263-3. Epub 2022 Mar 4. Cell Stress Chaperones. 2022. PMID: 35244890 Free PMC article.
Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.
Gallegos DA, Saurí J, Cohen RD, Wan X, Videau P, Vallota-Eastman AO, Shaala LA, Youssef DTA, Williamson RT, Martin GE, Philmus B, Sikora AE, Ishmael JE, McPhail KL. Gallegos DA, et al. Among authors: wan x. J Nat Prod. 2018 Jun 22;81(6):1417-1425. doi: 10.1021/acs.jnatprod.8b00117. Epub 2018 May 29. J Nat Prod. 2018. PMID: 29808677 Free PMC article.
5,716 results