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Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Osterman IA, Wieland M, Maviza TP, Lashkevich KA, Lukianov DA, Komarova ES, Zakalyukina YV, Buschauer R, Shiriaev DI, Leyn SA, Zlamal JE, Biryukov MV, Skvortsov DA, Tashlitsky VN, Polshakov VI, Cheng J, Polikanov YS, Bogdanov AA, Osterman AL, Dmitriev SE, Beckmann R, Dontsova OA, Wilson DN, Sergiev PV. Osterman IA, et al. Among authors: cheng j. Nat Chem Biol. 2020 Oct;16(10):1071-1077. doi: 10.1038/s41589-020-0578-x. Epub 2020 Jun 29. Nat Chem Biol. 2020. PMID: 32601485
Structure of the 80S ribosome-Xrn1 nuclease complex.
Tesina P, Heckel E, Cheng J, Fromont-Racine M, Buschauer R, Kater L, Beatrix B, Berninghausen O, Jacquier A, Becker T, Beckmann R. Tesina P, et al. Among authors: cheng j. Nat Struct Mol Biol. 2019 Apr;26(4):275-280. doi: 10.1038/s41594-019-0202-5. Epub 2019 Mar 25. Nat Struct Mol Biol. 2019. PMID: 30911188
Structural and mutational analysis of the ribosome-arresting human XBP1u.
Shanmuganathan V, Schiller N, Magoulopoulou A, Cheng J, Braunger K, Cymer F, Berninghausen O, Beatrix B, Kohno K, von Heijne G, Beckmann R. Shanmuganathan V, et al. Among authors: cheng j. Elife. 2019 Jun 27;8:e46267. doi: 10.7554/eLife.46267. Elife. 2019. PMID: 31246176 Free PMC article.
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