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The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation.
Sitapara RA, Gauthier AG, Valdés-Ferrer SI, Lin M, Patel V, Wang M, Martino AT, Perron JC, Ashby CR Jr, Tracey KJ, Pavlov VA, Mantell LL. Sitapara RA, et al. Among authors: tracey kj. Mol Med. 2020 Jun 29;26(1):63. doi: 10.1186/s10020-020-00177-z. Mol Med. 2020. PMID: 32600307 Free PMC article.
The cholinergic anti-inflammatory pathway.
Pavlov VA, Tracey KJ. Pavlov VA, et al. Among authors: tracey kj. Brain Behav Immun. 2005 Nov;19(6):493-9. doi: 10.1016/j.bbi.2005.03.015. Brain Behav Immun. 2005. PMID: 15922555 Review.
Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.
Lin X, Yang H, Sakuragi T, Hu M, Mantell LL, Hayashi S, Al-Abed Y, Tracey KJ, Ulloa L, Miller EJ. Lin X, et al. Among authors: tracey kj. Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L583-90. doi: 10.1152/ajplung.00091.2005. Epub 2005 Jun 3. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15937067 Free article.
ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis.
Al-Abed Y, Dabideen D, Aljabari B, Valster A, Messmer D, Ochani M, Tanovic M, Ochani K, Bacher M, Nicoletti F, Metz C, Pavlov VA, Miller EJ, Tracey KJ. Al-Abed Y, et al. Among authors: tracey kj. J Biol Chem. 2005 Nov 4;280(44):36541-4. doi: 10.1074/jbc.C500243200. Epub 2005 Aug 22. J Biol Chem. 2005. PMID: 16115897 Free article.
463 results