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The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis.
Krishn SR, Salem I, Quaglia F, Naranjo NM, Agarwal E, Liu Q, Sarker S, Kopenhaver J, McCue PA, Weinreb PH, Violette SM, Altieri DC, Languino LR. Krishn SR, et al. Among authors: violette sm. J Extracell Vesicles. 2020 May 20;9(1):1763594. doi: 10.1080/20013078.2020.1763594. eCollection 2020. J Extracell Vesicles. 2020. PMID: 32595914 Free PMC article.
αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor.
Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, FitzGerald TJ, Altieri DC, Languino LR. Lu H, et al. Among authors: violette sm. Cancer Res. 2016 Sep 1;76(17):5163-74. doi: 10.1158/0008-5472.CAN-16-0543. Epub 2016 Jul 22. Cancer Res. 2016. PMID: 27450452 Free PMC article.
Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.
Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR. Dutta A, et al. Among authors: violette sm. Cancer Res. 2014 Mar 1;74(5):1598-608. doi: 10.1158/0008-5472.CAN-13-1796. Epub 2014 Jan 2. Cancer Res. 2014. PMID: 24385215 Free PMC article.
Overexpression of the alphavbeta6 integrin in endometrial cancer.
Hecht JL, Dolinski BM, Gardner HA, Violette SM, Weinreb PH. Hecht JL, et al. Among authors: violette sm. Appl Immunohistochem Mol Morphol. 2008 Dec;16(6):543-7. doi: 10.1097/PAI.0b013e31816bc5ee. Appl Immunohistochem Mol Morphol. 2008. PMID: 18698261
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
Van Aarsen LA, Leone DR, Ho S, Dolinski BM, McCoon PE, LePage DJ, Kelly R, Heaney G, Rayhorn P, Reid C, Simon KJ, Horan GS, Tao N, Gardner HA, Skelly MM, Gown AM, Thomas GJ, Weinreb PH, Fawell SE, Violette SM. Van Aarsen LA, et al. Among authors: violette sm. Cancer Res. 2008 Jan 15;68(2):561-70. doi: 10.1158/0008-5472.CAN-07-2307. Cancer Res. 2008. PMID: 18199553
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β.
Geng H, Lan R, Singha PK, Gilchrist A, Weinreb PH, Violette SM, Weinberg JM, Saikumar P, Venkatachalam MA. Geng H, et al. Among authors: violette sm. Am J Pathol. 2012 Oct;181(4):1236-49. doi: 10.1016/j.ajpath.2012.06.035. Epub 2012 Aug 10. Am J Pathol. 2012. PMID: 22885106 Free PMC article.
82 results