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Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing.
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B. Zecha J, et al. Among authors: pichlmair a. Mol Cell Proteomics. 2020 Sep;19(9):1503-1522. doi: 10.1074/mcp.RA120.002164. Epub 2020 Jun 26. Mol Cell Proteomics. 2020. PMID: 32591346 Free PMC article.
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D. Lampl S, et al. Among authors: pichlmair a. J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26. J Hepatol. 2020. PMID: 32598967
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing.
Sadegh S, Matschinske J, Blumenthal DB, Galindez G, Kacprowski T, List M, Nasirigerdeh R, Oubounyt M, Pichlmair A, Rose TD, Salgado-Albarrán M, Späth J, Stukalov A, Wenke NK, Yuan K, Pauling JK, Baumbach J. Sadegh S, et al. Among authors: pichlmair a. Nat Commun. 2020 Jul 14;11(1):3518. doi: 10.1038/s41467-020-17189-2. Nat Commun. 2020. PMID: 32665542 Free PMC article.
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.
Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. Stukalov A, et al. Among authors: pichlmair a. Nature. 2021 Jun;594(7862):246-252. doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12. Nature. 2021. PMID: 33845483
Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs.
Manček-Keber M, Hafner-Bratkovič I, Lainšček D, Benčina M, Govednik T, Orehek S, Plaper T, Jazbec V, Bergant V, Grass V, Pichlmair A, Jerala R. Manček-Keber M, et al. Among authors: pichlmair a. FASEB J. 2021 Jun;35(6):e21651. doi: 10.1096/fj.202100560R. FASEB J. 2021. PMID: 34004056 Free PMC article.
Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators.
Pennemann FL, Mussabekova A, Urban C, Stukalov A, Andersen LL, Grass V, Lavacca TM, Holze C, Oubraham L, Benamrouche Y, Girardi E, Boulos RE, Hartmann R, Superti-Furga G, Habjan M, Imler JL, Meignin C, Pichlmair A. Pennemann FL, et al. Among authors: pichlmair a. Nat Commun. 2021 Dec 1;12(1):7009. doi: 10.1038/s41467-021-27192-w. Nat Commun. 2021. PMID: 34853303 Free PMC article.
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Ambike S, Cheng CC, Feuerherd M, Velkov S, Baldassi D, Afridi SQ, Porras-Gonzalez D, Wei X, Hagen P, Kneidinger N, Stoleriu MG, Grass V, Burgstaller G, Pichlmair A, Merkel OM, Ko C, Michler T. Ambike S, et al. Among authors: pichlmair a. Nucleic Acids Res. 2022 Jan 11;50(1):333-349. doi: 10.1093/nar/gkab1248. Nucleic Acids Res. 2022. PMID: 34928377 Free PMC article.
Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection.
Wagner KI, Mateyka LM, Jarosch S, Grass V, Weber S, Schober K, Hammel M, Burrell T, Kalali B, Poppert H, Beyer H, Schambeck S, Holdenrieder S, Strötges-Achatz A, Haselmann V, Neumaier M, Erber J, Priller A, Yazici S, Roggendorf H, Odendahl M, Tonn T, Dick A, Witter K, Mijočević H, Protzer U, Knolle PA, Pichlmair A, Crowell CS, Gerhard M, D'Ippolito E, Busch DH. Wagner KI, et al. Among authors: pichlmair a. Cell Rep. 2022 Jan 11;38(2):110214. doi: 10.1016/j.celrep.2021.110214. Epub 2021 Dec 17. Cell Rep. 2022. PMID: 34968416 Free PMC article.
ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.
Jocher G, Grass V, Tschirner SK, Riepler L, Breimann S, Kaya T, Oelsner M, Hamad MS, Hofmann LI, Blobel CP, Schmidt-Weber CB, Gokce O, Jakwerth CA, Trimpert J, Kimpel J, Pichlmair A, Lichtenthaler SF. Jocher G, et al. Among authors: pichlmair a. EMBO Rep. 2022 Jun 7;23(6):e54305. doi: 10.15252/embr.202154305. Epub 2022 May 8. EMBO Rep. 2022. PMID: 35527514 Free PMC article.
Cell-free production of personalized therapeutic phages targeting multidrug-resistant bacteria.
Emslander Q, Vogele K, Braun P, Stender J, Willy C, Joppich M, Hammerl JA, Abele M, Meng C, Pichlmair A, Ludwig C, Bugert JJ, Simmel FC, Westmeyer GG. Emslander Q, et al. Among authors: pichlmair a. Cell Chem Biol. 2022 Sep 15;29(9):1434-1445.e7. doi: 10.1016/j.chembiol.2022.06.003. Epub 2022 Jul 11. Cell Chem Biol. 2022. PMID: 35820417 Free article.
90 results