Mobley WC - Search Results

1

Reversing a model of Parkinson's disease with in situ converted nigral neurons.

Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD. Qian H, et al. Among authors: mobley wc. Nature. 2020 Jun;582(7813):550-556. doi: 10.1038/s41586-020-2388-4. Epub 2020 Jun 24. Nature. 2020. PMID: 32581380 Free PMC article.

2

Author Correction: Reversing a model of Parkinson's disease with in situ converted nigral neurons.

Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD. Qian H, et al. Among authors: mobley wc. Nature. 2020 Aug;584(7820):E17. doi: 10.1038/s41586-020-2583-3. Nature. 2020. PMID: 32724206

3

Potential use of γ-secretase modulators in the treatment of Alzheimer disease.

Wagner SL, Tanzi RE, Mobley WC, Galasko D. Wagner SL, et al. Among authors: mobley wc. Arch Neurol. 2012 Oct;69(10):1255-8. doi: 10.1001/archneurol.2012.540. Arch Neurol. 2012. PMID: 22801784 Free PMC article. Review.

4

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.

Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, Mu Y, Loo LS, Cai L, Thompson RC, Yang B, Chen Y, Johnson PF, Wu C, Bu G, Mobley WC, Zhang D, Gage FH, Ranscht B, Zhang YW, Lipton SA, Hong W, Xu H. Wang X, et al. Among authors: mobley wc. Nat Med. 2013 Apr;19(4):473-80. doi: 10.1038/nm.3117. Epub 2013 Mar 24. Nat Med. 2013. PMID: 23524343 Free PMC article.

5

Molecular studies in Alzheimer's disease.

Holtzman DM, Mobley WC. Holtzman DM, et al. Among authors: mobley wc. Trends Biochem Sci. 1991 Apr;16(4):140-4. doi: 10.1016/0968-0004(91)90056-2. Trends Biochem Sci. 1991. PMID: 1877089 Review.

6

NGF rescues hippocampal cholinergic neuronal markers, restores neurogenesis, and improves the spatial working memory in a mouse model of Huntington's Disease.

Zhang H, Petit GH, Gaughwin PM, Hansen C, Ranganathan S, Zuo X, Smith R, Roybon L, Brundin P, Mobley WC, Li JY. Zhang H, et al. Among authors: mobley wc. J Huntingtons Dis. 2013;2(1):69-82. doi: 10.3233/JHD-120026. J Huntingtons Dis. 2013. PMID: 25063430

7

Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome.

Chen XQ, Sawa M, Mobley WC. Chen XQ, et al. Among authors: mobley wc. Free Radic Biol Med. 2018 Jan;114:52-61. doi: 10.1016/j.freeradbiomed.2017.10.341. Epub 2017 Oct 12. Free Radic Biol Med. 2018. PMID: 29031834 Free PMC article. Review.

8

Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model.

Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Chen XQ, et al. Among authors: mobley wc. Alzheimers Dement. 2021 Feb;17(2):271-292. doi: 10.1002/alz.12185. Epub 2020 Sep 25. Alzheimers Dement. 2021. PMID: 32975365 Free PMC article.

9

Mouse model of neurodegeneration: atrophy of basal forebrain cholinergic neurons in trisomy 16 transplants.

Holtzman DM, Li YW, DeArmond SJ, McKinley MP, Gage FH, Epstein CJ, Mobley WC. Holtzman DM, et al. Among authors: mobley wc. Proc Natl Acad Sci U S A. 1992 Feb 15;89(4):1383-7. doi: 10.1073/pnas.89.4.1383. Proc Natl Acad Sci U S A. 1992. PMID: 1741393 Free PMC article.

10

Nerve growth factor in Alzheimer's disease: to treat or not to treat?

Mobley WC. Mobley WC. Neurobiol Aging. 1989 Sep-Oct;10(5):578-80; discussion 588-90. doi: 10.1016/0197-4580(89)90135-8. Neurobiol Aging. 1989. PMID: 2812231

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