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25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.
Gold ES, Diercks AH, Podolsky I, Podyminogin RL, Askovich PS, Treuting PM, Aderem A. Gold ES, et al. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10666-71. doi: 10.1073/pnas.1404271111. Epub 2014 Jul 3. Proc Natl Acad Sci U S A. 2014. PMID: 24994901 Free PMC article.
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.
Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, Beutler B, Aderem A. Zak DE, et al. Among authors: gold es. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11536-41. doi: 10.1073/pnas.1107577108. Epub 2011 Jun 27. Proc Natl Acad Sci U S A. 2011. PMID: 21709223 Free PMC article.
The macrophage--a cell for all seasons.
Morrissette N, Gold E, Aderem A. Morrissette N, et al. Trends Cell Biol. 1999 May;9(5):199-201. doi: 10.1016/s0962-8924(99)01540-8. Trends Cell Biol. 1999. PMID: 10357607 Review. No abstract available.
27 results