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Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study.
Rahman MA, Brekke J, Arnesen V, Hannisdal MH, Navarro AG, Waha A, Herfindal L, Rygh CB, Bratland E, Brandal P, Haasz J, Oltedal L, Miletic H, Lundervold A, Lie SA, Goplen D, Chekenya M. Rahman MA, et al. Among authors: chekenya m. Immun Inflamm Dis. 2020 Sep;8(3):342-359. doi: 10.1002/iid3.315. Epub 2020 Jun 24. Immun Inflamm Dis. 2020. PMID: 32578964 Free PMC article. Clinical Trial.
A reproducible brain tumour model established from human glioblastoma biopsies.
Wang J, Miletic H, Sakariassen PØ, Huszthy PC, Jacobsen H, Brekkå N, Li X, Zhao P, Mørk S, Chekenya M, Bjerkvig R, Enger PØ. Wang J, et al. Among authors: chekenya m. BMC Cancer. 2009 Dec 29;9:465. doi: 10.1186/1471-2407-9-465. BMC Cancer. 2009. PMID: 20040089 Free PMC article.
Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma.
Svendsen A, Verhoeff JJ, Immervoll H, Brøgger JC, Kmiecik J, Poli A, Netland IA, Prestegarden L, Planagumà J, Torsvik A, Kjersem AB, Sakariassen PØ, Heggdal JI, Van Furth WR, Bjerkvig R, Lund-Johansen M, Enger PØ, Felsberg J, Brons NH, Tronstad KJ, Waha A, Chekenya M. Svendsen A, et al. Among authors: chekenya m. Acta Neuropathol. 2011 Oct;122(4):495-510. doi: 10.1007/s00401-011-0867-2. Epub 2011 Aug 24. Acta Neuropathol. 2011. PMID: 21863242 Free PMC article.
Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level.
Kmiecik J, Poli A, Brons NH, Waha A, Eide GE, Enger PØ, Zimmer J, Chekenya M. Kmiecik J, et al. Among authors: chekenya m. J Neuroimmunol. 2013 Nov 15;264(1-2):71-83. doi: 10.1016/j.jneuroim.2013.08.013. Epub 2013 Aug 31. J Neuroimmunol. 2013. PMID: 24045166 Free article.
Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma.
Rygh CB, Wang J, Thuen M, Gras Navarro A, Huuse EM, Thorsen F, Poli A, Zimmer J, Haraldseth O, Lie SA, Enger PØ, Chekenya M. Rygh CB, et al. Among authors: chekenya m. PLoS One. 2014 Sep 30;9(9):e108414. doi: 10.1371/journal.pone.0108414. eCollection 2014. PLoS One. 2014. PMID: 25268630 Free PMC article.
Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients.
Dominguez-Valentin M, Gras Navarro A, Rahman AM, Kumar S, Retière C, Ulvestad E, Kristensen V, Lund-Johansen M, Lie BA, Enger PØ, Njølstad G, Kristoffersen E, Lie SA, Chekenya M. Dominguez-Valentin M, et al. Among authors: chekenya m. Cancer Res. 2016 Sep 15;76(18):5326-36. doi: 10.1158/0008-5472.CAN-16-1162. Epub 2016 Jul 12. Cancer Res. 2016. PMID: 27406829
Increased infiltration and tolerised antigen-specific CD8+ TEM cells in tumor but not peripheral blood have no impact on survival of HCMV+ glioblastoma patients.
Bahador M, Gras Navarro A, Rahman MA, Dominguez-Valentin M, Sarowar S, Ulvestad E, Njølstad G, Lie SA, Kristoffersen EK, Bratland E, Chekenya M. Bahador M, et al. Among authors: chekenya m. Oncoimmunology. 2017 Jun 5;6(8):e1336272. doi: 10.1080/2162402X.2017.1336272. eCollection 2017. Oncoimmunology. 2017. PMID: 28919997 Free PMC article.
Glioblastoma Stem-Like Cells Are More Susceptible Than Differentiated Cells to Natural Killer Cell Lysis Mediated Through Killer Immunoglobulin-Like Receptors-Human Leukocyte Antigen Ligand Mismatch and Activation Receptor-Ligand Interactions.
Haspels HN, Rahman MA, Joseph JV, Gras Navarro A, Chekenya M. Haspels HN, et al. Among authors: chekenya m. Front Immunol. 2018 Jun 18;9:1345. doi: 10.3389/fimmu.2018.01345. eCollection 2018. Front Immunol. 2018. PMID: 29967607 Free PMC article.
40 results