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Insulin-like growth factors I and II are autocrine factors in stimulating proteoglycan synthesis, a marker of differentiated chondrocytes, acting through their respective receptors on a clonal human chondrosarcoma-derived chondrocyte cell line, HCS-2/8.
Takigawa M, Okawa T, Pan H, Aoki C, Takahashi K, Zue J, Suzuki F, Kinoshita A. Takigawa M, et al. Endocrinology. 1997 Oct;138(10):4390-400. doi: 10.1210/endo.138.10.5265. Endocrinology. 1997. PMID: 9322955
Physiological role of vitamin A in growth cartilage cells: low concentrations of retinoic acid strongly promote the proliferation of rabbit costal growth cartilage cells in culture.
Enomoto M, Pan H, Suzuki F, Takigawa M. Enomoto M, et al. Among authors: takigawa m. J Biochem. 1990 May;107(5):743-8. doi: 10.1093/oxfordjournals.jbchem.a123119. J Biochem. 1990. PMID: 2398039 Free article.
We have demonstrated that high concentrations of retinoic acid (RA) inhibit expression of the differentiated phenotypes of rabbit costal chondrocytes in culture [M. Takigawa et al. (1980) Proc. Natl. Acad. Sci. U.S. 77, 1481-1485]. ...This stimulatory effect was obs …
We have demonstrated that high concentrations of retinoic acid (RA) inhibit expression of the differentiated phenotypes of rabbit costal cho …
1,044 results