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Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites.
Wort SJ, Ito M, Chou PC, Mc Master SK, Badiger R, Jazrawi E, de Souza P, Evans TW, Mitchell JA, Pinhu L, Ito K, Adcock IM. Wort SJ, et al. J Biol Chem. 2009 Sep 4;284(36):24297-305. doi: 10.1074/jbc.M109.032524. Epub 2009 Jul 10. J Biol Chem. 2009. PMID: 19592490 Free PMC article.
Extracorporeal carbon dioxide removal to "protect" the lung.
Stirling SL, Cordingley JJ, Hunter DN, Griffiths MJ, Wort SJ, Evans TW, Finney SJ. Stirling SL, et al. Among authors: wort sj. Thorax. 2009 Aug;64(8):726-7. doi: 10.1136/thx.2008.098731. Thorax. 2009. PMID: 19638565
Pathophysiology of pulmonary hypertension in acute lung injury.
Price LC, McAuley DF, Marino PS, Finney SJ, Griffiths MJ, Wort SJ. Price LC, et al. Among authors: wort sj. Am J Physiol Lung Cell Mol Physiol. 2012 May 1;302(9):L803-15. doi: 10.1152/ajplung.00355.2011. Epub 2012 Jan 13. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22246001 Free PMC article. Review.
Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.
Price LC, Caramori G, Perros F, Meng C, Gambaryan N, Dorfmuller P, Montani D, Casolari P, Zhu J, Dimopoulos K, Shao D, Girerd B, Mumby S, Proudfoot A, Griffiths M, Papi A, Humbert M, Adcock IM, Wort SJ. Price LC, et al. Among authors: wort sj. PLoS One. 2013 Oct 4;8(10):e75415. doi: 10.1371/journal.pone.0075415. eCollection 2013. PLoS One. 2013. PMID: 24124488 Free PMC article.
Evidence for the involvement of type I interferon in pulmonary arterial hypertension.
George PM, Oliver E, Dorfmuller P, Dubois OD, Reed DM, Kirkby NS, Mohamed NA, Perros F, Antigny F, Fadel E, Schreiber BE, Holmes AM, Southwood M, Hagan G, Wort SJ, Bartlett N, Morrell NW, Coghlan JG, Humbert M, Zhao L, Mitchell JA. George PM, et al. Among authors: wort sj. Circ Res. 2014 Feb 14;114(4):677-88. doi: 10.1161/CIRCRESAHA.114.302221. Epub 2013 Dec 13. Circ Res. 2014. PMID: 24334027 Free PMC article.
184 results