Thapa S - Search Results

1

An astrocyte cell line that differentially propagates murine prions.

Tahir W, Abdulrahman B, Abdelaziz DH, Thapa S, Walia R, Schätzl HM. Tahir W, et al. Among authors: thapa s. J Biol Chem. 2020 Aug 14;295(33):11572-11583. doi: 10.1074/jbc.RA120.012596. Epub 2020 Jun 19. J Biol Chem. 2020. PMID: 32561641 Free PMC article.

2

Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro.

Abdelaziz DH, Thapa S, Abdulrahman B, Lu L, Jain S, Schatzl HM. Abdelaziz DH, et al. Among authors: thapa s. Sci Rep. 2017 Sep 5;7(1):10538. doi: 10.1038/s41598-017-11235-8. Sci Rep. 2017. PMID: 28874781 Free PMC article.

3

The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions.

Abdulrahman BA, Abdelaziz D, Thapa S, Lu L, Jain S, Gilch S, Proniuk S, Zukiwski A, Schatzl HM. Abdulrahman BA, et al. Among authors: thapa s. Sci Rep. 2017 Dec 14;7(1):17565. doi: 10.1038/s41598-017-17770-8. Sci Rep. 2017. PMID: 29242534 Free PMC article.

4

Dimerization of the cellular prion protein inhibits propagation of scrapie prions.

Engelke AD, Gonsberg A, Thapa S, Jung S, Ulbrich S, Seidel R, Basu S, Multhaup G, Baier M, Engelhard M, Schätzl HM, Winklhofer KF, Tatzelt J. Engelke AD, et al. Among authors: thapa s. J Biol Chem. 2018 May 25;293(21):8020-8031. doi: 10.1074/jbc.RA117.000990. Epub 2018 Apr 10. J Biol Chem. 2018. PMID: 29636413 Free PMC article.

5

Overexpression of quality control proteins reduces prion conversion in prion-infected cells.

Thapa S, Abdulrahman B, Abdelaziz DH, Lu L, Ben Aissa M, Schatzl HM. Thapa S, et al. J Biol Chem. 2018 Oct 12;293(41):16069-16082. doi: 10.1074/jbc.RA118.002754. Epub 2018 Aug 28. J Biol Chem. 2018. PMID: 30154245 Free PMC article.

6

Recombinant prion protein vaccination of transgenic elk PrP mice and reindeer overcomes self-tolerance and protects mice against chronic wasting disease.

Abdelaziz DH, Thapa S, Brandon J, Maybee J, Vankuppeveld L, McCorkell R, Schätzl HM. Abdelaziz DH, et al. Among authors: thapa s. J Biol Chem. 2018 Dec 21;293(51):19812-19822. doi: 10.1074/jbc.RA118.004810. Epub 2018 Nov 5. J Biol Chem. 2018. PMID: 30397182 Free PMC article.

7

Metformin reduces prion infection in neuronal cells by enhancing autophagy.

Abdelaziz DH, Thapa S, Abdulrahman B, Vankuppeveld L, Schatzl HM. Abdelaziz DH, et al. Among authors: thapa s. Biochem Biophys Res Commun. 2020 Mar 5;523(2):423-428. doi: 10.1016/j.bbrc.2019.12.074. Epub 2019 Dec 23. Biochem Biophys Res Commun. 2020. PMID: 31874705

8

Sephin1 Reduces Prion Infection in Prion-Infected Cells and Animal Model.

Thapa S, Abdelaziz DH, Abdulrahman BA, Schatzl HM. Thapa S, et al. Mol Neurobiol. 2020 May;57(5):2206-2219. doi: 10.1007/s12035-020-01880-y. Epub 2020 Jan 24. Mol Neurobiol. 2020. PMID: 31981074

9

Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis.

Arifin MI, Hannaoui S, Chang SC, Thapa S, Schatzl HM, Gilch S. Arifin MI, et al. Among authors: thapa s. Int J Mol Sci. 2021 Feb 25;22(5):2271. doi: 10.3390/ijms22052271. Int J Mol Sci. 2021. PMID: 33668798 Free PMC article. Review.

10

Astrocyte in prion disease: a double-edged sword.

Tahir W, Thapa S, Schatzl HM. Tahir W, et al. Among authors: thapa s. Neural Regen Res. 2022 Aug;17(8):1659-1665. doi: 10.4103/1673-5374.332202. Neural Regen Res. 2022. PMID: 35017412 Free PMC article. Review.

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