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Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer.
Zurlo G, Liu X, Takada M, Fan C, Simon JM, Ptacek TS, Rodriguez J, von Kriegsheim A, Liu J, Locasale JW, Robinson A, Zhang J, Holler JM, Kim B, Zikánová M, Bierau J, Xie L, Chen X, Li M, Perou CM, Zhang Q. Zurlo G, et al. Among authors: simon jm. Nat Commun. 2019 Nov 15;10(1):5177. doi: 10.1038/s41467-019-13168-4. Nat Commun. 2019. PMID: 31729379 Free PMC article.
Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss.
Liu X, Simon JM, Xie H, Hu L, Wang J, Zurlo G, Fan C, Ptacek TS, Herring L, Tan X, Li M, Baldwin AS, Kim WY, Wu T, Kirschner MW, Gong K, Zhang Q. Liu X, et al. Among authors: simon jm. Mol Cell. 2020 Mar 19;77(6):1294-1306.e5. doi: 10.1016/j.molcel.2020.01.009. Epub 2020 Feb 4. Mol Cell. 2020. PMID: 32023483 Free PMC article.
USP37 promotes deubiquitination of HIF2α in kidney cancer.
Hong K, Hu L, Liu X, Simon JM, Ptacek TS, Zheng X, Liao C, Baldwin AS, Zhang Q. Hong K, et al. Among authors: simon jm. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):13023-13032. doi: 10.1073/pnas.2002567117. Epub 2020 May 27. Proc Natl Acad Sci U S A. 2020. PMID: 32461361 Free PMC article.
A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.
Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Mulvaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, Major MB. Bowman BM, et al. Among authors: simon jm. J Pathol. 2020 Oct;252(2):125-137. doi: 10.1002/path.5504. Epub 2020 Aug 29. J Pathol. 2020. PMID: 32619021 Free PMC article.
Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer.
Liao C, Zhang Y, Fan C, Herring LE, Liu J, Locasale JW, Takada M, Zhou J, Zurlo G, Hu L, Simon JM, Ptacek TS, Andrianov VG, Loza E, Peng Y, Yang H, Perou CM, Zhang Q. Liao C, et al. Among authors: simon jm. Cancer Discov. 2020 Nov;10(11):1706-1721. doi: 10.1158/2159-8290.CD-20-0288. Epub 2020 Jul 20. Cancer Discov. 2020. PMID: 32690540 Free PMC article.
329 results