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BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei.
Oppenheim RD, Creek DJ, Macrae JI, Modrzynska KK, Pino P, Limenitakis J, Polonais V, Seeber F, Barrett MP, Billker O, McConville MJ, Soldati-Favre D. Oppenheim RD, et al. Among authors: creek dj. PLoS Pathog. 2014 Jul 17;10(7):e1004263. doi: 10.1371/journal.ppat.1004263. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 25032958 Free PMC article.
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.
Tjhin ET, Spry C, Sewell AL, Hoegl A, Barnard L, Sexton AE, Siddiqui G, Howieson VM, Maier AG, Creek DJ, Strauss E, Marquez R, Auclair K, Saliba KJ. Tjhin ET, et al. Among authors: creek dj. PLoS Pathog. 2018 Apr 3;14(4):e1006918. doi: 10.1371/journal.ppat.1006918. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29614109 Free PMC article.
Retargeting azithromycin analogues to have dual-modality antimalarial activity.
Burns AL, Sleebs BE, Siddiqui G, De Paoli AE, Anderson D, Liffner B, Harvey R, Beeson JG, Creek DJ, Goodman CD, McFadden GI, Wilson DW. Burns AL, et al. Among authors: creek dj. BMC Biol. 2020 Sep 29;18(1):133. doi: 10.1186/s12915-020-00859-4. BMC Biol. 2020. PMID: 32993629 Free PMC article.
Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
Devine SM, Challis MP, Kigotho JK, Siddiqui G, De Paoli A, MacRaild CA, Avery VM, Creek DJ, Norton RS, Scammells PJ. Devine SM, et al. Among authors: creek dj. Eur J Med Chem. 2021 Oct 5;221:113518. doi: 10.1016/j.ejmech.2021.113518. Epub 2021 May 13. Eur J Med Chem. 2021. PMID: 34058708
139 results