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PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.
Peña-Oyarzun D, Rodriguez-Peña M, Burgos-Bravo F, Vergara A, Kretschmar C, Sotomayor-Flores C, Ramirez-Sarmiento CA, De Smedt H, Reyes M, Perez W, Torres VA, Morselli E, Altamirano F, Wilson CAM, Hill JA, Lavandero S, Criollo A. Peña-Oyarzun D, et al. Among authors: sotomayor flores c. Autophagy. 2021 Jul;17(7):1714-1728. doi: 10.1080/15548627.2020.1782035. Epub 2020 Jun 30. Autophagy. 2021. PMID: 32543276 Free PMC article.
Polycystin-2-dependent control of cardiomyocyte autophagy.
Criollo A, Altamirano F, Pedrozo Z, Schiattarella GG, Li DL, Rivera-Mejías P, Sotomayor-Flores C, Parra V, Villalobos E, Battiprolu PK, Jiang N, May HI, Morselli E, Somlo S, de Smedt H, Gillette TG, Lavandero S, Hill JA. Criollo A, et al. Among authors: sotomayor flores c. J Mol Cell Cardiol. 2018 May;118:110-121. doi: 10.1016/j.yjmcc.2018.03.002. Epub 2018 Mar 6. J Mol Cell Cardiol. 2018. PMID: 29518398
Alteration in mitochondrial Ca(2+) uptake disrupts insulin signaling in hypertrophic cardiomyocytes.
Gutiérrez T, Parra V, Troncoso R, Pennanen C, Contreras-Ferrat A, Vasquez-Trincado C, Morales PE, Lopez-Crisosto C, Sotomayor-Flores C, Chiong M, Rothermel BA, Lavandero S. Gutiérrez T, et al. Among authors: sotomayor flores c. Cell Commun Signal. 2014 Nov 7;12:68. doi: 10.1186/s12964-014-0068-4. Cell Commun Signal. 2014. PMID: 25376904 Free PMC article.
Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway.
Sotomayor-Flores C, Rivera-Mejías P, Vásquez-Trincado C, López-Crisosto C, Morales PE, Pennanen C, Polakovicova I, Aliaga-Tobar V, García L, Roa JC, Rothermel BA, Maracaja-Coutinho V, Ho-Xuan H, Meister G, Chiong M, Ocaranza MP, Corvalán AH, Parra V, Lavandero S. Sotomayor-Flores C, et al. Cell Death Differ. 2020 Sep;27(9):2586-2604. doi: 10.1038/s41418-020-0522-3. Epub 2020 Mar 9. Cell Death Differ. 2020. PMID: 32152556 Free PMC article.
Up next: The dawn of systems biology in HFpEF research.
Bode D, Sotomayor-Flores C, Schiattarella GG. Bode D, et al. Among authors: sotomayor flores c. J Mol Cell Cardiol. 2022 Jul;168:96-97. doi: 10.1016/j.yjmcc.2022.04.016. Epub 2022 Apr 27. J Mol Cell Cardiol. 2022. PMID: 35489386 No abstract available.
Cardiac metabolism in HFpEF: from fuel to signalling.
Capone F, Sotomayor-Flores C, Bode D, Wang R, Rodolico D, Strocchi S, Schiattarella GG. Capone F, et al. Among authors: sotomayor flores c. Cardiovasc Res. 2023 Feb 3;118(18):3556-3575. doi: 10.1093/cvr/cvac166. Cardiovasc Res. 2023. PMID: 36504368