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Absence of SCAPER causes male infertility in humans and Drosophila by modulating microtubule dynamics during meiosis.
Wormser O, Levy Y, Bakhrat A, Bonaccorsi S, Graziadio L, Gatti M, AbuMadighem A, McKenney RJ, Okada K, El Riati S, Har-Vardi I, Huleihel M, Levitas E, Birk OS, Abdu U. Wormser O, et al. Among authors: mckenney rj. J Med Genet. 2021 Apr;58(4):254-263. doi: 10.1136/jmedgenet-2020-106946. Epub 2020 Jun 11. J Med Genet. 2021. PMID: 32527956 Free PMC article.
The tail wags the motor.
McKenney RJ. McKenney RJ. Nat Chem Biol. 2019 Nov;15(11):1033-1034. doi: 10.1038/s41589-019-0367-6. Nat Chem Biol. 2019. PMID: 31501591 No abstract available.
The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Bodrug T, Wilson-Kubalek EM, Nithianantham S, Thompson AF, Alfieri A, Gaska I, Major J, Debs G, Inagaki S, Gutierrez P, Gheber L, McKenney RJ, Sindelar CV, Milligan R, Stumpff J, Rosenfeld SS, Forth ST, Al-Bassam J. Bodrug T, et al. Among authors: mckenney rj. Elife. 2020 Jan 20;9:e51131. doi: 10.7554/eLife.51131. Elife. 2020. PMID: 31958056 Free PMC article.
45 results