Guenther DC - Search Results

1

Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes.

Guenther DC, Emehiser RG, Inskeep A, Karmakar S, Hrdlicka PJ. Guenther DC, et al. Org Biomol Chem. 2020 Jun 24;18(24):4645-4655. doi: 10.1039/d0ob01052a. Org Biomol Chem. 2020. PMID: 32520054 Free PMC article.

2

Pyrene-functionalized triazole-linked 2'-deoxyuridines-probes for discrimination of single nucleotide polymorphisms (SNPs).

Østergaard ME, Guenther DC, Kumar P, Baral B, Deobald L, Paszczynski AJ, Sharma PK, Hrdlicka PJ. Østergaard ME, et al. Among authors: guenther dc. Chem Commun (Camb). 2010 Jul 21;46(27):4929-31. doi: 10.1039/c0cc01133a. Epub 2010 Jun 4. Chem Commun (Camb). 2010. PMID: 20526503

3

Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA.

Sau SP, Madsen AS, Podbevsek P, Andersen NK, Kumar TS, Andersen S, Rathje RL, Anderson BA, Guenther DC, Karmakar S, Kumar P, Plavec J, Wengel J, Hrdlicka PJ. Sau SP, et al. Among authors: guenther dc. J Org Chem. 2013 Oct 4;78(19):9560-70. doi: 10.1021/jo4015936. Epub 2013 Sep 25. J Org Chem. 2013. PMID: 24032477 Free PMC article.

4

Recognition of mixed-sequence DNA duplexes: design guidelines for invaders based on 2'-O-(pyren-1-yl)methyl-RNA monomers.

Karmakar S, Guenther DC, Hrdlicka PJ. Karmakar S, et al. Among authors: guenther dc. J Org Chem. 2013 Dec 6;78(23):12040-8. doi: 10.1021/jo402085v. Epub 2013 Nov 20. J Org Chem. 2013. PMID: 24195730 Free PMC article.

5

C5-alkynyl-functionalized α-L-LNA: synthesis, thermal denaturation experiments and enzymatic stability.

Kumar P, Baral B, Anderson BA, Guenther DC, Østergaard ME, Sharma PK, Hrdlicka PJ. Kumar P, et al. Among authors: guenther dc. J Org Chem. 2014 Jun 6;79(11):5062-73. doi: 10.1021/jo5006153. Epub 2014 May 13. J Org Chem. 2014. PMID: 24797769 Free PMC article.

6

Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid).

Kumar P, Østergaard ME, Baral B, Anderson BA, Guenther DC, Kaura M, Raible DJ, Sharma PK, Hrdlicka PJ. Kumar P, et al. Among authors: guenther dc. J Org Chem. 2014 Jun 6;79(11):5047-61. doi: 10.1021/jo500614a. Epub 2014 May 13. J Org Chem. 2014. PMID: 24825249 Free PMC article.

7

Carbohydrate-functionalized locked nucleic acids: oligonucleotides with extraordinary binding affinity, target specificity, and enzymatic stability.

Kaura M, Guenther DC, Hrdlicka PJ. Kaura M, et al. Among authors: guenther dc. Org Lett. 2014 Jun 20;16(12):3308-11. doi: 10.1021/ol501306u. Epub 2014 Jun 3. Org Lett. 2014. PMID: 24890872

8

Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O2'-alkylated RNA monomers.

Karmakar S, Madsen AS, Guenther DC, Gibbons BC, Hrdlicka PJ. Karmakar S, et al. Among authors: guenther dc. Org Biomol Chem. 2014 Oct 21;12(39):7758-73. doi: 10.1039/c4ob01183j. Epub 2014 Aug 21. Org Biomol Chem. 2014. PMID: 25144705 Free PMC article.

9

Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles.

Guenther DC, Karmakar S, Hrdlicka PJ. Guenther DC, et al. Chem Commun (Camb). 2015 Oct 18;51(81):15051-4. doi: 10.1039/c5cc06264k. Chem Commun (Camb). 2015. PMID: 26314212 Free PMC article.

10

Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2'-triphenylene- and coronene-functionalized RNA monomers.

Karmakar S, Guenther DC, Gibbons BC, Hrdlicka PJ. Karmakar S, et al. Among authors: guenther dc. Org Biomol Chem. 2017 Nov 15;15(44):9362-9371. doi: 10.1039/c7ob01920c. Org Biomol Chem. 2017. PMID: 29090304 Free PMC article.

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