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The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14433-14443. doi: 10.1073/pnas.2000497117. Epub 2020 Jun 8.
Proc Natl Acad Sci U S A. 2020.
PMID: 32513747
Free PMC article.
Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila.
Beyrakhova KA, van Straaten K, Li L, Boniecki MT, Anderson DH, Cygler M.
Beyrakhova KA, et al.
J Biol Chem. 2016 Jul 22;291(30):15767-77. doi: 10.1074/jbc.M115.708701. Epub 2016 May 17.
J Biol Chem. 2016.
PMID: 27226543
Free PMC article.
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Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
Zhao J, Beyrakhova K, Liu Y, Alvarez CP, Bueler SA, Xu L, Xu C, Boniecki MT, Kanelis V, Luo ZQ, Cygler M, Rubinstein JL.
Zhao J, et al. Among authors: beyrakhova k.
PLoS Pathog. 2017 Jun 1;13(6):e1006394. doi: 10.1371/journal.ppat.1006394. eCollection 2017 Jun.
PLoS Pathog. 2017.
PMID: 28570695
Free PMC article.
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Legionella pneumophila effector Lem4 is a membrane-associated protein tyrosine phosphatase.
Beyrakhova K, Li L, Xu C, Gagarinova A, Cygler M.
Beyrakhova K, et al.
J Biol Chem. 2018 Aug 24;293(34):13044-13058. doi: 10.1074/jbc.RA118.003845. Epub 2018 Jul 5.
J Biol Chem. 2018.
PMID: 29976756
Free PMC article.
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Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host.
Grishin AM, Beyrakhova KA, Cygler M.
Grishin AM, et al. Among authors: beyrakhova ka.
Protein Sci. 2015 May;24(5):604-20. doi: 10.1002/pro.2636. Epub 2015 Feb 6.
Protein Sci. 2015.
PMID: 25565677
Free PMC article.
Review.
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Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10.
Boddy KC, Zhu H, D'Costa VM, Xu C, Beyrakhova K, Cygler M, Grinstein S, Coyaud E, Laurent EMN, St-Germain J, Raught B, Brumell JH.
Boddy KC, et al. Among authors: beyrakhova k.
Nat Commun. 2021 Aug 4;12(1):4707. doi: 10.1038/s41467-021-24983-z.
Nat Commun. 2021.
PMID: 34349110
Free PMC article.
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Antiangiogenic and antivascular effects of a recombinant tumstatin-derived peptide in a corneal neovascularization model.
Esipov R, Beyrakhova K, Likhvantseva V, Stepanova E, Stepanenko V, Kostromina M, Abramchik Y, Miroshnikov A.
Esipov R, et al. Among authors: beyrakhova k.
Biochimie. 2012 Jun;94(6):1368-75. doi: 10.1016/j.biochi.2012.03.007. Epub 2012 Mar 14.
Biochimie. 2012.
PMID: 22440655
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Production of thymosin alpha1 via non-enzymatic acetylation of the recombinant precursor.
Esipov RS, Stepanenko VN, Beyrakhova KA, Muravjeva TI, Miroshnikov AI.
Esipov RS, et al. Among authors: beyrakhova ka.
Biotechnol Appl Biochem. 2010 May 19;56(1):17-25. doi: 10.1042/BA20100027.
Biotechnol Appl Biochem. 2010.
PMID: 20408810
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