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ASCT2 is the primary serine transporter in cancer cells.
Conger KO, Chidley C, Ozgurses ME, Zhao H, Kim Y, Semina SE, Burns P, Rawat V, Sheldon R, Ben-Sahra I, Frasor J, Sorger PK, DeNicola GM, Coloff JL. Conger KO, et al. Among authors: sorger pk. bioRxiv [Preprint]. 2023 Oct 11:2023.10.09.561530. doi: 10.1101/2023.10.09.561530. bioRxiv. 2023. PMID: 37873453 Free PMC article. Preprint.
A general algorithm for consensus 3D cell segmentation from 2D segmented stacks.
Zhou FY, Yapp C, Shang Z, Daetwyler S, Marin Z, Islam MT, Nanes BA, Jenkins E, Gihana GM, Chang BJ, Weems A, Dustin M, Morrison SJ, Fiolka RP, Dean KM, Jamieson A, Sorger PK, Danuser GK. Zhou FY, et al. Among authors: sorger pk. bioRxiv [Preprint]. 2024 May 6:2024.05.03.592249. doi: 10.1101/2024.05.03.592249. bioRxiv. 2024. PMID: 38766074 Free PMC article. Preprint.
OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization.
Ahdritz G, Bouatta N, Floristean C, Kadyan S, Xia Q, Gerecke W, O'Donnell TJ, Berenberg D, Fisk I, Zanichelli N, Zhang B, Nowaczynski A, Wang B, Stepniewska-Dziubinska MM, Zhang S, Ojewole A, Guney ME, Biderman S, Watkins AM, Ra S, Lorenzo PR, Nivon L, Weitzner B, Ban YA, Chen S, Zhang M, Li C, Song SL, He Y, Sorger PK, Mostaque E, Zhang Z, Bonneau R, AlQuraishi M. Ahdritz G, et al. Among authors: sorger pk. Nat Methods. 2024 May 14. doi: 10.1038/s41592-024-02272-z. Online ahead of print. Nat Methods. 2024. PMID: 38744917
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation.
Rogava M, Aprati TJ, Chi WY, Melms JC, Hug C, Davis SH, Earlie EM, Chung C, Deshmukh SK, Wu S, Sledge G, Tang S, Ho P, Amin AD, Caprio L, Gurjao C, Tagore S, Ngo B, Lee MJ, Zanetti G, Wang Y, Chen S, Ge W, Melo LMN, Allies G, Rösler J, Gibney GT, Schmitz OJ, Sykes M, Creusot RJ, Tüting T, Schadendorf D, Röcken M, Eigentler TK, Molotkov A, Mintz A, Bakhoum SF, Beyaz S, Cantley LC, Sorger PK, Meckelmann SW, Tasdogan A, Liu D, Laughney AM, Izar B. Rogava M, et al. Among authors: sorger pk. Nat Cancer. 2024 Mar;5(3):433-447. doi: 10.1038/s43018-023-00704-x. Epub 2024 Jan 29. Nat Cancer. 2024. PMID: 38286827
Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity.
Zhang X, Pant SM, Ritch CC, Tang HY, Shao H, Dweep H, Gong YY, Brooks R, Brafford P, Wolpaw AJ, Lee Y, Weeraratna A, Sehgal A, Herlyn M, Kossenkov A, Speicher D, Sorger PK, Santagata S, Dang CV. Zhang X, et al. Among authors: sorger pk. Nat Commun. 2024 Jan 20;15(1):633. doi: 10.1038/s41467-024-44778-2. Nat Commun. 2024. PMID: 38245503 Free PMC article.
305 results