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Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D'Amico G, Parsons M, Harwood C, Meier P, Hodivala-Dilke KM. Lechertier T, et al. Nat Commun. 2020 Jun 4;11(1):2810. doi: 10.1038/s41467-020-16618-6. Nat Commun. 2020. PMID: 32499572 Free PMC article.
Focal adhesion kinase and tumour angiogenesis.
Lechertier T, Hodivala-Dilke K. Lechertier T, et al. J Pathol. 2012 Jan;226(2):404-12. doi: 10.1002/path.3018. Epub 2011 Nov 23. J Pathol. 2012. PMID: 21984450 Review.
Use of the mouse aortic ring assay to study angiogenesis.
Baker M, Robinson SD, Lechertier T, Barber PR, Tavora B, D'Amico G, Jones DT, Vojnovic B, Hodivala-Dilke K. Baker M, et al. Among authors: lechertier t. Nat Protoc. 2011 Dec 22;7(1):89-104. doi: 10.1038/nprot.2011.435. Nat Protoc. 2011. PMID: 22193302
Gene expression analysis in human breast cancer associated blood vessels.
Jones DT, Lechertier T, Mitter R, Herbert JM, Bicknell R, Jones JL, Li JL, Buffa F, Harris AL, Hodivala-Dilke K. Jones DT, et al. Among authors: lechertier t. PLoS One. 2012;7(10):e44294. doi: 10.1371/journal.pone.0044294. Epub 2012 Oct 2. PLoS One. 2012. PMID: 23056178 Free PMC article.
FAK-heterozygous mice display enhanced tumour angiogenesis.
Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR, Hodivala-Dilke K. Kostourou V, et al. Among authors: lechertier t. Nat Commun. 2013;4:2020. doi: 10.1038/ncomms3020. Nat Commun. 2013. PMID: 23799510 Free PMC article.
Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.
Tavora B, Reynolds LE, Batista S, Demircioglu F, Fernandez I, Lechertier T, Lees DM, Wong PP, Alexopoulou A, Elia G, Clear A, Ledoux A, Hunter J, Perkins N, Gribben JG, Hodivala-Dilke KM. Tavora B, et al. Among authors: lechertier t. Nature. 2014 Oct 2;514(7520):112-6. doi: 10.1038/nature13541. Epub 2014 Jul 27. Nature. 2014. PMID: 25079333 Free PMC article.
A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma.
Dvorkina M, Nieddu V, Chakelam S, Pezzolo A, Cantilena S, Leite AP, Chayka O, Regad T, Pistorio A, Sementa AR, Virasami A, Barton J, Montano X, Lechertier T, Brindle N, Morgenstern D, Lebras M, Burns AJ, Saunders NJ, Hodivala-Dilke K, Bagella L, De The H, Anderson J, Sebire N, Pistoia V, Sala A, Salomoni P. Dvorkina M, et al. Among authors: lechertier t. Clin Cancer Res. 2016 Jul 1;22(13):3398-409. doi: 10.1158/1078-0432.CCR-15-2081. Epub 2016 Apr 13. Clin Cancer Res. 2016. PMID: 27076624
Dual role of pericyte α6β1-integrin in tumour blood vessels.
Reynolds LE, D'Amico G, Lechertier T, Papachristodoulou A, Muñoz-Félix JM, De Arcangelis A, Baker M, Serrels B, Hodivala-Dilke KM. Reynolds LE, et al. Among authors: lechertier t. J Cell Sci. 2017 May 1;130(9):1583-1595. doi: 10.1242/jcs.197848. Epub 2017 Mar 13. J Cell Sci. 2017. PMID: 28289267 Free PMC article.
18 results