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Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests.
Álvarez-Rodríguez B, Tiede C, Hoste ACR, Surtees RA, Trinh CH, Slack GS, Chamberlain J, Hewson R, Fresco A, Sastre P, Tomlinson DC, Millner PA, Edwards TA, Barr JN. Álvarez-Rodríguez B, et al. Among authors: trinh ch. PLoS Negl Trop Dis. 2020 Jun 3;14(6):e0008364. doi: 10.1371/journal.pntd.0008364. eCollection 2020 Jun. PLoS Negl Trop Dis. 2020. PMID: 32492018 Free PMC article.
Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation.
Tanner SJ, Ariza A, Richard CA, Kyle HF, Dods RL, Blondot ML, Wu W, Trincão J, Trinh CH, Hiscox JA, Carroll MW, Silman NJ, Eléouët JF, Edwards TA, Barr JN. Tanner SJ, et al. Among authors: trinh ch. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1580-5. doi: 10.1073/pnas.1317262111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24434552 Free PMC article.
The crystal structure of the Hazara virus nucleocapsid protein.
Surtees R, Ariza A, Punch EK, Trinh CH, Dowall SD, Hewson R, Hiscox JA, Barr JN, Edwards TA. Surtees R, et al. Among authors: trinh ch. BMC Struct Biol. 2015 Dec 29;15:24. doi: 10.1186/s12900-015-0051-3. BMC Struct Biol. 2015. PMID: 26715309 Free PMC article.
Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.
Hughes DJ, Tiede C, Penswick N, Tang AA, Trinh CH, Mandal U, Zajac KZ, Gaule T, Howell G, Edwards TA, Duan J, Feyfant E, McPherson MJ, Tomlinson DC, Whitehouse A. Hughes DJ, et al. Among authors: trinh ch. Sci Signal. 2017 Nov 14;10(505):eaaj2005. doi: 10.1126/scisignal.aaj2005. Sci Signal. 2017. PMID: 29138295 Free PMC article.
The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex.
Selvaraj M, Yegambaram K, Todd EJAA, Richard CA, Dods RL, Pangratiou GM, Trinh CH, Moul SL, Murphy JC, Mankouri J, Éléouët JF, Barr JN, Edwards TA. Selvaraj M, et al. Among authors: trinh ch. mBio. 2018 Nov 13;9(6):e01554-18. doi: 10.1128/mBio.01554-18. mBio. 2018. PMID: 30425144 Free PMC article.
RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site.
Haza KZ, Martin HL, Rao A, Turner AL, Saunders SE, Petersen B, Tiede C, Tipping K, Tang AA, Ajayi M, Taylor T, Harvey M, Fishwick KM, Adams TL, Gaule TG, Trinh CH, Johnson M, Breeze AL, Edwards TA, McPherson MJ, Tomlinson DC. Haza KZ, et al. Among authors: trinh ch. Nat Commun. 2021 Jun 30;12(1):4045. doi: 10.1038/s41467-021-24316-0. Nat Commun. 2021. PMID: 34193876 Free PMC article.
49 results