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Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus.
Delavallée L, Mathiah N, Cabon L, Mazeraud A, Brunelle-Navas MN, Lerner LK, Tannoury M, Prola A, Moreno-Loshuertos R, Baritaud M, Vela L, Garbin K, Garnier D, Lemaire C, Langa-Vives F, Cohen-Salmon M, Fernández-Silva P, Chrétien F, Migeotte I, Susin SA. Delavallée L, et al. Among authors: lerner lk. Mol Metab. 2020 Oct;40:101027. doi: 10.1016/j.molmet.2020.101027. Epub 2020 May 30. Mol Metab. 2020. PMID: 32480041 Free PMC article.
del(8p) and TNFRSF10B loss are associated with a poor prognosis and resistance to fludarabine in chronic lymphocytic leukemia.
Jondreville L, Dehgane L, Doualle C, Smagghe L, Grange B, Davi F, Lerner LK, Garnier D, Bravetti C, Tournilhac O, Roos-Weil D, Boubaya M, Chapiro E, Susin SA, Nguyen-Khac F. Jondreville L, et al. Among authors: lerner lk. Leukemia. 2023 Nov;37(11):2221-2230. doi: 10.1038/s41375-023-02035-3. Epub 2023 Sep 26. Leukemia. 2023. PMID: 37752286
A genetic cluster of patients with variant xeroderma pigmentosum with two different founder mutations.
Munford V, Castro LP, Souto R, Lerner LK, Vilar JB, Quayle C, Asif H, Schuch AP, de Souza TA, Ienne S, Alves FIA, Moura LMS, Galante PAF, Camargo AA, Liboredo R, Pena SDJ, Sarasin A, Chaibub SC, Menck CFM. Munford V, et al. Among authors: lerner lk. Br J Dermatol. 2017 May;176(5):1270-1278. doi: 10.1111/bjd.15084. Epub 2017 Mar 22. Br J Dermatol. 2017. PMID: 27664908
Filling gaps in translesion DNA synthesis in human cells.
Quinet A, Lerner LK, Martins DJ, Menck CFM. Quinet A, et al. Among authors: lerner lk. Mutat Res Genet Toxicol Environ Mutagen. 2018 Dec;836(Pt B):127-142. doi: 10.1016/j.mrgentox.2018.02.004. Epub 2018 Feb 23. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 30442338 Review.
16 results