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BAX 855, a PEGylated rFVIII product with prolonged half-life. Development, functional and structural characterisation.
Turecek PL, Bossard MJ, Graninger M, Gritsch H, Höllriegl W, Kaliwoda M, Matthiessen P, Mitterer A, Muchitsch EM, Purtscher M, Rottensteiner H, Schiviz A, Schrenk G, Siekmann J, Varadi K, Riley T, Ehrlich HJ, Schwarz HP, Scheiflinger F. Turecek PL, et al. Among authors: schrenk g. Hamostaseologie. 2012;32 Suppl 1:S29-38. Hamostaseologie. 2012. PMID: 22961422
Affinity of FVIII-specific antibodies reveals major differences between neutralizing and nonneutralizing antibodies in humans.
Hofbauer CJ, Whelan SF, Hirschler M, Allacher P, Horling FM, Lawo JP, Oldenburg J, Tiede A, Male C, Windyga J, Greinacher A, Knöbl PN, Schrenk G, Koehn J, Scheiflinger F, Reipert BM. Hofbauer CJ, et al. Among authors: schrenk g. Blood. 2015 Feb 12;125(7):1180-8. doi: 10.1182/blood-2014-09-598268. Epub 2014 Dec 16. Blood. 2015. PMID: 25515962 Free article.
Nonacog gamma, a novel recombinant factor IX with low factor IXa content for treatment and prophylaxis of bleeding episodes.
Turecek PL, Abbühl B, Tangada SD, Chapman M, Gritsch H, Rottensteiner H, Schrenk G, Mitterer A, Dietrich B, Höllriegl W, Schiviz A, Horling F, Reipert BM, Muchitsch EM, Pavlova BG, Scheiflinger F. Turecek PL, et al. Among authors: schrenk g. Expert Rev Clin Pharmacol. 2015 Mar;8(2):163-77. doi: 10.1586/17512433.2015.1011126. Epub 2015 Feb 8. Expert Rev Clin Pharmacol. 2015. PMID: 25660348
A bio-inspired method for direct measurement of local wall shear rates with micrometer localization using the multimeric protein von Willebrand factor as sensor molecule.
Bonazza K, Scheichl B, Frank J, Rottensteiner H, Schrenk G, Friedbacher G, Turecek PL, Scheiflinger F, Allmaier G. Bonazza K, et al. Among authors: schrenk g. Biomicrofluidics. 2017 Aug 30;11(4):044117. doi: 10.1063/1.5000503. eCollection 2017 Jul. Biomicrofluidics. 2017. PMID: 28936275 Free PMC article.
Evaluation of Factor VIII Polysialylation: Identification of a Longer-Acting Experimental Therapy in Mice and Monkeys.
Glantschnig H, Bauer A, Benamara K, Dockal M, Ehrlich V, Gritsch H, Höbarth G, Horling FM, Kopic A, Leidenmühler P, Reipert BM, Rottensteiner H, Ruthsatz T, Schrenk G, Schuster M, Turecek PL, Weber A, Wolfsegger M, Scheiflinger F, Höllriegl W. Glantschnig H, et al. Among authors: schrenk g. J Pharmacol Exp Ther. 2019 Oct;371(1):95-105. doi: 10.1124/jpet.119.260067. Epub 2019 Jul 31. J Pharmacol Exp Ther. 2019. PMID: 31366602
Evidence of protective effects of recombinant ADAMTS13 in a humanized model of sickle cell disease.
Rossato P, Federti E, Matte A, Glantschnig H, Canneva F, Schuster M, Coulibaly S, Schrenk G, Voelkel D, Dockal M, Plaimauer B, Andolfo I, Iolascon A, Rottensteiner H, Gritsch H, Scheiflinger F, Hoellriegl W, Franceschi L. Rossato P, et al. Among authors: schrenk g. Haematologica. 2022 Nov 1;107(11):2650-2660. doi: 10.3324/haematol.2021.280233. Haematologica. 2022. PMID: 35443560 Free PMC article.
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