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Correcting thrombin generation ex vivo using different haemostatic agents following cardiac surgery requiring the use of cardiopulmonary bypass.
Percy CL, Hartmann R, Jones RM, Balachandran S, Mehta D, Dockal M, Scheiflinger F, O'Donnell VB, Hall JE, Collins PW. Percy CL, et al. Among authors: hartmann r. Blood Coagul Fibrinolysis. 2015 Jun;26(4):357-67. doi: 10.1097/MBC.0000000000000243. Blood Coagul Fibrinolysis. 2015. PMID: 25928274 Free PMC article.
Small peptides blocking inhibition of factor Xa and tissue factor-factor VIIa by tissue factor pathway inhibitor (TFPI).
Dockal M, Hartmann R, Fries M, Thomassen MC, Heinzmann A, Ehrlich H, Rosing J, Osterkamp F, Polakowski T, Reineke U, Griessner A, Brandstetter H, Scheiflinger F. Dockal M, et al. Among authors: hartmann r. J Biol Chem. 2014 Jan 17;289(3):1732-41. doi: 10.1074/jbc.M113.533836. Epub 2013 Nov 25. J Biol Chem. 2014. PMID: 24275667 Free PMC article.
Factor IX mutants with enhanced catalytic activity.
Hartmann R, Dockal M, Kammlander W, Panholzer E, Nicolaes GA, Fiedler C, Rosing J, Scheiflinger F. Hartmann R, et al. J Thromb Haemost. 2009 Oct;7(10):1656-62. doi: 10.1111/j.1538-7836.2009.03560.x. Epub 2009 Jul 28. J Thromb Haemost. 2009. PMID: 19656280 Free article.
Role of exosite binding modulators in the inhibition of Fxa by TFPI.
Peraramelli S, Thomassen S, Heinzmann A, Hackeng TM, Hartmann R, Scheiflinger F, Dockal M, Rosing J. Peraramelli S, et al. Among authors: hartmann r. Thromb Haemost. 2016 Mar;115(3):580-90. doi: 10.1160/TH15-04-0354. Epub 2015 Nov 26. Thromb Haemost. 2016. PMID: 26607136
Direct inhibition of factor VIIa by TFPI and TFPI constructs.
Peraramelli S, Thomassen S, Heinzmann A, Rosing J, Hackeng TM, Hartmann R, Scheiflinger F, Dockal M. Peraramelli S, et al. Among authors: hartmann r. J Thromb Haemost. 2013 Apr;11(4):704-14. doi: 10.1111/jth.12152. J Thromb Haemost. 2013. PMID: 23347185 Free article.
1,246 results