Schutte R - Search Results

1

Identification of small molecules by screening a mixture-based scaffold compound library for treatment of alpha-1 antitrypsin deficiency.

Zhang X, Santos R, Debevec G, Li D, Schutte R, Pham K, Liu C, Ostrov DA, Giulianotti M. Zhang X, et al. Among authors: schutte r. Biochem Biophys Res Commun. 2020 Jun 18;527(1):317-323. doi: 10.1016/j.bbrc.2020.04.037. Epub 2020 May 11. Biochem Biophys Res Commun. 2020. PMID: 32446387

2

Targeting the site encoded by SERPINA1*E342K for treating alpha-1 antitrypsin deficiency-associated liver diseases.

Zhang X, Pham K, Li D, Schutte RJ, Brantly M, Liu C, Ostrov DA. Zhang X, et al. FEBS Lett. 2019 Jul;593(14):1849-1862. doi: 10.1002/1873-3468.13452. Epub 2019 Jun 6. FEBS Lett. 2019. PMID: 31116417 Free article.

3

A Novel Small Molecule Inhibits Intrahepatocellular Accumulation of Z-Variant Alpha 1-Antitrypsin In Vitro and In Vivo.

Zhang X, Pham K, Li D, Schutte RJ, Gonzalo DH, Zhang P, Oshins R, Tan W, Brantly M, Liu C, Ostrov DA. Zhang X, et al. Among authors: schutte rj. Cells. 2019 Dec 6;8(12):1586. doi: 10.3390/cells8121586. Cells. 2019. PMID: 31817705 Free PMC article.

4

Molecular docking predictions of fragrance binding to human leukocyte antigen molecules.

Schutte RJ, Zhang X, An N, Ostrov DA, Vukmanović S. Schutte RJ, et al. Contact Dermatitis. 2019 Sep;81(3):174-183. doi: 10.1111/cod.13283. Epub 2019 Jul 9. Contact Dermatitis. 2019. PMID: 30957232

5

Human Leukocyte Antigen Associations in Drug Hypersensitivity Reactions.

Schutte RJ, Sun Y, Li D, Zhang F, Ostrov DA. Schutte RJ, et al. Clin Lab Med. 2018 Dec;38(4):669-677. doi: 10.1016/j.cll.2018.08.002. Clin Lab Med. 2018. PMID: 30420060 Review.

6

Identification of drug-specific public TCR driving severe cutaneous adverse reactions.

Pan RY, Chu MT, Wang CW, Lee YS, Lemonnier F, Michels AW, Schutte R, Ostrov DA, Chen CB, Phillips EJ, Mallal SA, Mockenhaupt M, Bellón T, Tassaneeyakul W, White KD, Roujeau JC, Chung WH, Hung SI. Pan RY, et al. Among authors: schutte r. Nat Commun. 2019 Aug 8;10(1):3569. doi: 10.1038/s41467-019-11396-2. Nat Commun. 2019. PMID: 31395875 Free PMC article.

7

Structural Elements Recognized by Abacavir-Induced T Cells.

Yerly D, Pompeu YA, Schutte RJ, Eriksson KK, Strhyn A, Bracey AW, Buus S, Ostrov DA. Yerly D, et al. Int J Mol Sci. 2017 Jul 7;18(7):1464. doi: 10.3390/ijms18071464. Int J Mol Sci. 2017. PMID: 28686208 Free PMC article.

8

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors.

Ratnayake WS, Apostolatos CA, Apostolatos AH, Schutte RJ, Huynh MA, Ostrov DA, Acevedo-Duncan M. Ratnayake WS, et al. Cell Adh Migr. 2018;12(5):447-463. doi: 10.1080/19336918.2018.1471323. Epub 2018 May 21. Cell Adh Migr. 2018. PMID: 29781749 Free PMC article.

9

Human Leukocyte Antigen B*14:01 and B*35:01 Are Associated With Trimethoprim-Sulfamethoxazole Induced Liver Injury.

Li YJ, Phillips EJ, Dellinger A, Nicoletti P, Schutte R, Li D, Ostrov DA, Fontana RJ, Watkins PB, Stolz A, Daly AK, Aithal GP, Barnhart H, Chalasani N; Drug-induced Liver Injury Network. Li YJ, et al. Among authors: schutte r. Hepatology. 2021 Jan;73(1):268-281. doi: 10.1002/hep.31258. Hepatology. 2021. PMID: 32270503 Free PMC article.

10

HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.

Konvinse KC, Trubiano JA, Pavlos R, James I, Shaffer CM, Bejan CA, Schutte RJ, Ostrov DA, Pilkinton MA, Rosenbach M, Zwerner JP, Williams KB, Bourke J, Martinez P, Rwandamuriye F, Chopra A, Watson M, Redwood AJ, White KD, Mallal SA, Phillips EJ. Konvinse KC, et al. Among authors: schutte rj. J Allergy Clin Immunol. 2019 Jul;144(1):183-192. doi: 10.1016/j.jaci.2019.01.045. Epub 2019 Feb 16. J Allergy Clin Immunol. 2019. PMID: 30776417 Free PMC article.

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