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Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors.
Kovacikova K, Gorostiola González M, Jones R, Reguera J, Gigante A, Pérez-Pérez MJ, Pürstinger G, Moesslacher J, Langer T, Jeong LS, Delang L, Neyts J, Snijder EJ, van Westen GJP, van Hemert MJ. Kovacikova K, et al. Among authors: purstinger g. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0256620. doi: 10.1128/AAC.02566-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33875421 Free PMC article.
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Musiu S, Pürstinger G, Stallinger S, Vrancken R, Haegeman A, Koenen F, Leyssen P, Froeyen M, Neyts J, Paeshuyse J. Musiu S, et al. Among authors: purstinger g. Antiviral Res. 2014 Jun;106:71-9. doi: 10.1016/j.antiviral.2014.03.010. Epub 2014 Mar 27. Antiviral Res. 2014. PMID: 24680957
Potential use of antiviral agents in polio eradication.
De Palma AM, Pürstinger G, Wimmer E, Patick AK, Andries K, Rombaut B, De Clercq E, Neyts J. De Palma AM, et al. Among authors: purstinger g. Emerg Infect Dis. 2008 Apr;14(4):545-51. doi: 10.3201/eid1404.070439. Emerg Infect Dis. 2008. PMID: 18394270 Free PMC article.
Substituted imidazopyridines as potent inhibitors of HCV replication.
Vliegen I, Paeshuyse J, De Burghgraeve T, Lehman LS, Paulson M, Shih IH, Mabery E, Boddeker N, De Clercq E, Reiser H, Oare D, Lee WA, Zhong W, Bondy S, Pürstinger G, Neyts J. Vliegen I, et al. Among authors: purstinger g. J Hepatol. 2009 May;50(5):999-1009. doi: 10.1016/j.jhep.2008.12.028. Epub 2009 Feb 26. J Hepatol. 2009. PMID: 19303654 Free PMC article.
The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C.
De Palma AM, Heggermont W, Lanke K, Coutard B, Bergmann M, Monforte AM, Canard B, De Clercq E, Chimirri A, Pürstinger G, Rohayem J, van Kuppeveld F, Neyts J. De Palma AM, et al. Among authors: purstinger g. J Virol. 2008 May;82(10):4720-30. doi: 10.1128/JVI.01338-07. Epub 2008 Mar 12. J Virol. 2008. PMID: 18337578 Free PMC article.
22 results