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107 results

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Page 1
Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria.
St Jean PL, Koh GCKW, Breton JJ, Espino FEJ, Hien TT, Krudsood S, Lacerda MVG, Llanos-Cuentas A, Lon C, Mohammed R, Namaik-Larp CS, Pereira DB, Saunders DL, Velez ID, Yilma D, Villegas MF, Duparc S, Green JA. St Jean PL, et al. Among authors: duparc s. Pharmacogenet Genomics. 2020 Sep;30(7):161-165. doi: 10.1097/FPC.0000000000000407. Pharmacogenet Genomics. 2020. PMID: 32433338 Free PMC article.
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial.
Chandiwana N, Kruger C, Johnstone H, Chughlay MF, Ju C, Kim B, Dineka Y, Arbe-Barnes S, Miller R, Owen A, Hill A, Windgassen D, Abla N, Marrast AC, Duparc S, Francois Venter WD. Chandiwana N, et al. Among authors: duparc s. EBioMedicine. 2022 Dec;86:104322. doi: 10.1016/j.ebiom.2022.104322. Epub 2022 Nov 1. EBioMedicine. 2022. PMID: 36332361 Free PMC article. Clinical Trial.
Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study.
Llanos-Cuentas A, Lacerda MV, Rueangweerayut R, Krudsood S, Gupta SK, Kochar SK, Arthur P, Chuenchom N, Möhrle JJ, Duparc S, Ugwuegbulam C, Kleim JP, Carter N, Green JA, Kellam L. Llanos-Cuentas A, et al. Among authors: duparc s. Lancet. 2014 Mar 22;383(9922):1049-58. doi: 10.1016/S0140-6736(13)62568-4. Epub 2013 Dec 19. Lancet. 2014. PMID: 24360369 Clinical Trial.
Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial.
Phyo AP, Jittamala P, Nosten FH, Pukrittayakamee S, Imwong M, White NJ, Duparc S, Macintyre F, Baker M, Möhrle JJ. Phyo AP, et al. Among authors: duparc s. Lancet Infect Dis. 2016 Jan;16(1):61-69. doi: 10.1016/S1473-3099(15)00320-5. Epub 2015 Oct 5. Lancet Infect Dis. 2016. PMID: 26448141 Free PMC article. Clinical Trial.
Estimation of the Antirelapse Efficacy of Tafenoquine, Using Plasmodium vivax Genotyping.
Beck HP, Wampfler R, Carter N, Koh G, Osorio L, Rueangweerayut R, Krudsood S, Lacerda MV, Llanos-Cuentas A, Duparc S, Rubio JP, Green JA. Beck HP, et al. Among authors: duparc s. J Infect Dis. 2016 Mar 1;213(5):794-9. doi: 10.1093/infdis/jiv508. Epub 2015 Oct 23. J Infect Dis. 2016. PMID: 26500351 Free PMC article. Clinical Trial.
Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial.
St Jean PL, Xue Z, Carter N, Koh GC, Duparc S, Taylor M, Beaumont C, Llanos-Cuentas A, Rueangweerayut R, Krudsood S, Green JA, Rubio JP. St Jean PL, et al. Among authors: duparc s. Malar J. 2016 Feb 18;15:97. doi: 10.1186/s12936-016-1145-5. Malar J. 2016. PMID: 26888075 Free PMC article. Clinical Trial.
Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects.
Green JA, Mohamed K, Goyal N, Bouhired S, Hussaini A, Jones SW, Koh GC, Kostov I, Taylor M, Wolstenholm A, Duparc S. Green JA, et al. Among authors: duparc s. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7321-7332. doi: 10.1128/AAC.01588-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27697758 Free PMC article. Clinical Trial.
Diagnosis and Treatment of Plasmodium vivax Malaria.
Baird JK, Valecha N, Duparc S, White NJ, Price RN. Baird JK, et al. Among authors: duparc s. Am J Trop Med Hyg. 2016 Dec 28;95(6 Suppl):35-51. doi: 10.4269/ajtmh.16-0171. Epub 2016 Oct 5. Am J Trop Med Hyg. 2016. PMID: 27708191 Free PMC article.
Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers.
Rueangweerayut R, Bancone G, Harrell EJ, Beelen AP, Kongpatanakul S, Möhrle JJ, Rousell V, Mohamed K, Qureshi A, Narayan S, Yubon N, Miller A, Nosten FH, Luzzatto L, Duparc S, Kleim JP, Green JA. Rueangweerayut R, et al. Among authors: duparc s. Am J Trop Med Hyg. 2017 Sep;97(3):702-711. doi: 10.4269/ajtmh.16-0779. Epub 2017 Jul 27. Am J Trop Med Hyg. 2017. PMID: 28749773 Free PMC article.
107 results