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In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts.
Imhof D, Anghel N, Winzer P, Balmer V, Ramseier J, Hänggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Imhof D, et al. Among authors: balmer v. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:90-101. doi: 10.1016/j.ijpddr.2021.05.001. Epub 2021 May 18. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34030110 Free PMC article.
Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo.
Anghel N, Imhof D, Winzer P, Balmer V, Ramseier J, Haenggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Anghel N, et al. Among authors: balmer v. Int J Parasitol Drugs Drug Resist. 2021 Dec;17:92-106. doi: 10.1016/j.ijpddr.2021.08.007. Epub 2021 Aug 28. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34482255 Free PMC article.
In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum.
Winzer P, Müller J, Aguado-Martínez A, Rahman M, Balmer V, Manser V, Ortega-Mora LM, Ojo KK, Fan E, Maly DJ, Van Voorhis WC, Hemphill A. Winzer P, et al. Among authors: balmer v. Antimicrob Agents Chemother. 2015 Oct;59(10):6361-74. doi: 10.1128/AAC.01236-15. Epub 2015 Jul 27. Antimicrob Agents Chemother. 2015. PMID: 26248379 Free PMC article.
Two Novel Calcium-Dependent Protein Kinase 1 Inhibitors Interfere with Vertical Transmission in Mice Infected with Neospora caninum Tachyzoites.
Müller J, Aguado-Martínez A, Balmer V, Maly DJ, Fan E, Ortega-Mora LM, Ojo KK, Van Voorhis WC, Hemphill A. Müller J, et al. Among authors: balmer v. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02324-16. doi: 10.1128/AAC.02324-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28137808 Free PMC article.
Assessment of the Activity of Decoquinate and Its Quinoline-O-Carbamate Derivatives against Toxoplasma gondii In Vitro and in Pregnant Mice Infected with T. gondii Oocysts.
Ramseier J, Imhof D, Anghel N, Hänggeli K, Beteck RM, Balmer V, Ortega-Mora LM, Sanchez-Sanchez R, Ferre I, Haynes RK, Hemphill A. Ramseier J, et al. Among authors: balmer v. Molecules. 2021 Oct 22;26(21):6393. doi: 10.3390/molecules26216393. Molecules. 2021. PMID: 34770802 Free PMC article.
Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice.
Müller J, Aguado-Martinez A, Manser V, Balmer V, Winzer P, Ritler D, Hostettler I, Arranz-Solís D, Ortega-Mora L, Hemphill A. Müller J, et al. Among authors: balmer v. Int J Parasitol Drugs Drug Resist. 2015 Feb 13;5(1):16-25. doi: 10.1016/j.ijpddr.2015.02.001. eCollection 2015 Apr. Int J Parasitol Drugs Drug Resist. 2015. PMID: 25941626 Free PMC article.
In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites.
Jiménez-Meléndez A, Ojo KK, Wallace AM, Smith TR, Hemphill A, Balmer V, Regidor-Cerrillo J, Ortega-Mora LM, Hehl AB, Fan E, Maly DJ, Van Voorhis WC, Álvarez-García G. Jiménez-Meléndez A, et al. Among authors: balmer v. Int J Parasitol. 2017 Oct;47(12):811-821. doi: 10.1016/j.ijpara.2017.08.005. Epub 2017 Sep 9. Int J Parasitol. 2017. PMID: 28899692
29 results