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Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease.
Mitsialis V, Wall S, Liu P, Ordovas-Montanes J, Parmet T, Vukovic M, Spencer D, Field M, McCourt C, Toothaker J, Bousvaros A; Boston Children’s Hospital Inflammatory Bowel Disease Center; Brigham and Women’s Hospital Crohn’s and Colitis Center; Shalek AK, Kean L, Horwitz B, Goldsmith J, Tseng G, Snapper SB, Konnikova L. Mitsialis V, et al. Among authors: tseng g. Gastroenterology. 2020 Aug;159(2):591-608.e10. doi: 10.1053/j.gastro.2020.04.074. Epub 2020 May 16. Gastroenterology. 2020. PMID: 32428507 Free PMC article.
In utero human intestine harbors unique metabolome, including bacterial metabolites.
Li Y, Toothaker JM, Ben-Simon S, Ozeri L, Schweitzer R, McCourt BT, McCourt CC, Werner L, Snapper SB, Shouval DS, Khatib S, Koren O, Agnihorti S, Tseng G, Konnikova L. Li Y, et al. Among authors: tseng g. JCI Insight. 2020 Nov 5;5(21):e138751. doi: 10.1172/jci.insight.138751. JCI Insight. 2020. PMID: 33001863 Free PMC article.
CD16+CD163+ monocytes traffic to sites of inflammation during necrotizing enterocolitis in premature infants.
Olaloye OO, Liu P, Toothaker JM, McCourt BT, McCourt CC, Xiao J, Prochaska E, Shaffer S, Werner L; UPMC NICU Faculty; UPMC Pediatric Surgery Faculty; Gringauz J, Good M, Goldsmith JD, An X, Wang F, Snapper SB, Shouval D, Chen K, Tseng G, Konnikova L. Olaloye OO, et al. Among authors: tseng g. J Exp Med. 2021 Sep 6;218(9):e20200344. doi: 10.1084/jem.20200344. Epub 2021 Jul 16. J Exp Med. 2021. PMID: 34269788 Free PMC article.
Immune landscape of human placental villi using single-cell analysis.
Toothaker JM, Olaloye O, McCourt BT, McCourt CC, Silva TN, Case RM, Liu P, Yimlamai D, Tseng G, Konnikova L. Toothaker JM, et al. Among authors: tseng g. Development. 2022 Apr 15;149(8):dev200013. doi: 10.1242/dev.200013. Epub 2022 Feb 17. Development. 2022. PMID: 35050308 Free PMC article.
Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors.
Zhu L, Narloch JL, Onkar S, Joy M, Broadwater G, Luedke C, Hall A, Kim R, Pogue-Geile K, Sammons S, Nayyar N, Chukwueke U, Brastianos PK, Anders CK, Soloff AC, Vignali DAA, Tseng GC, Emens LA, Lucas PC, Blackwell KL, Oesterreich S, Lee AV. Zhu L, et al. Among authors: tseng gc. J Immunother Cancer. 2019 Oct 18;7(1):265. doi: 10.1186/s40425-019-0755-1. J Immunother Cancer. 2019. PMID: 31627744 Free PMC article.
465 results