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Page 1
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M. Bunse L, et al. Nat Med. 2018 Aug;24(8):1192-1203. doi: 10.1038/s41591-018-0095-6. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988124
An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny.
Roig-Merino A, Urban M, Bozza M, Peterson JD, Bullen L, Büchler-Schäff M, Stäble S, van der Hoeven F, Müller-Decker K, McKay TR, Milsom MD, Harbottle RP. Roig-Merino A, et al. Among authors: harbottle rp. Stem Cell Reports. 2022 Jan 11;17(1):143-158. doi: 10.1016/j.stemcr.2021.11.011. Epub 2021 Dec 22. Stem Cell Reports. 2022. PMID: 34942088 Free PMC article.
Delivery of non-viral naked DNA vectors to liver in small weaned pigs by hydrodynamic retrograde intrabiliary injection.
Chan T, Grisch-Chan HM, Schmierer P, Subotic U, Rimann N, Scherer T, Hetzel U, Bozza M, Harbottle R, Williams JA, Steblaj B, Ringer SK, Häberle J, Sidler X, Thöny B. Chan T, et al. Mol Ther Methods Clin Dev. 2022 Jan 19;24:268-279. doi: 10.1016/j.omtm.2022.01.006. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35211639 Free PMC article.
Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs.
Hongu T, Pein M, Insua-Rodríguez J, Gutjahr E, Mattavelli G, Meier J, Decker K, Descot A, Bozza M, Harbottle R, Trumpp A, Sinn HP, Riedel A, Oskarsson T. Hongu T, et al. Nat Cancer. 2022 Apr;3(4):486-504. doi: 10.1038/s43018-022-00353-6. Epub 2022 Apr 25. Nat Cancer. 2022. PMID: 35469015 Free PMC article.
Sustained expression from DNA vectors.
Wong SP, Argyros O, Harbottle RP. Wong SP, et al. Among authors: harbottle rp. Adv Genet. 2015;89:113-152. doi: 10.1016/bs.adgen.2014.11.002. Epub 2014 Dec 18. Adv Genet. 2015. PMID: 25620010 Review.
Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice.
Viarisio D, Müller-Decker K, Accardi R, Robitaille A, Dürst M, Beer K, Jansen L, Flechtenmacher C, Bozza M, Harbottle R, Voegele C, Ardin M, Zavadil J, Caldeira S, Gissmann L, Tommasino M. Viarisio D, et al. PLoS Pathog. 2018 Jan 11;14(1):e1006783. doi: 10.1371/journal.ppat.1006783. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29324843 Free PMC article.
Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors.
Thornton CD, Fielding S, Karbowniczek K, Roig-Merino A, Burrows AE, FitzPatrick LM, Sharaireh A, Tite JP, Mole SE, Harbottle RP, Caproni LJ, McKay TR. Thornton CD, et al. Among authors: harbottle rp. Mol Ther Methods Clin Dev. 2021 Oct 5;23:348-358. doi: 10.1016/j.omtm.2021.09.018. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34729381 Free PMC article.
54 results