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Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M. Bunse L, et al. Nat Med. 2018 Aug;24(8):1192-1203. doi: 10.1038/s41591-018-0095-6. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988124
TCR validation toward gene therapy for cancer.
Green EW, Bunse L, Bozza M, Sanghvi K, Platten M. Green EW, et al. Methods Enzymol. 2019;629:419-441. doi: 10.1016/bs.mie.2019.10.010. Epub 2019 Nov 6. Methods Enzymol. 2019. PMID: 31727252
NLGN4X TCR transgenic T cells to treat gliomas.
Krämer C, Kilian M, Chih YC, Kourtesakis A, Hoffmann DC, Boschert T, Koopmann P, Sanghvi K, De Roia A, Jung S, Jähne K, Day B, Shultz LD, Ratliff M, Harbottle R, Green EW, Will R, Wick W, Platten M, Bunse L. Krämer C, et al. Among authors: green ew. Neuro Oncol. 2024 Feb 2;26(2):266-278. doi: 10.1093/neuonc/noad172. Neuro Oncol. 2024. PMID: 37715782 Free PMC article.
Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy.
Tan CL, Lindner K, Boschert T, Meng Z, Rodriguez Ehrenfried A, De Roia A, Haltenhof G, Faenza A, Imperatore F, Bunse L, Lindner JM, Harbottle RP, Ratliff M, Offringa R, Poschke I, Platten M, Green EW. Tan CL, et al. Among authors: green ew. Nat Biotechnol. 2024 Mar 7. doi: 10.1038/s41587-024-02161-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38454173
Common T-Cell-Receptor Motifs and Features in Patients with Cytomegalovirus (CMV)-Seronegative End-Stage Renal Disease Receiving a Peptide Vaccination against CMV.
Bunse L, Sommerer C, Tan CL, Korell F, Schmitt A, Hückelhoven-Krauss A, Neuber B, Mertens T, Platten M, Green EW, Zeier M, Schmitt M. Bunse L, et al. Among authors: green ew. Int J Mol Sci. 2022 Jan 18;23(3):1029. doi: 10.3390/ijms23031029. Int J Mol Sci. 2022. PMID: 35162953 Free PMC article.
Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes.
Blobner J, Kilian M, Tan CL, Aslan K, Sanghvi K, Meyer J, Fischer M, Jähne K, Breckwoldt MO, Sahm F, von Deimling A, Bendszus M, Wick W, Platten M, Green E, Bunse L. Blobner J, et al. Neurooncol Adv. 2021 Sep 28;3(1):vdab147. doi: 10.1093/noajnl/vdab147. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34738084 Free PMC article.
High-throughput discovery of cancer-targeting TCRs.
Bunse L, Green EW, Platten M. Bunse L, et al. Among authors: green ew. Methods Enzymol. 2019;629:401-417. doi: 10.1016/bs.mie.2019.10.009. Epub 2019 Nov 6. Methods Enzymol. 2019. PMID: 31727251
117 results