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Complete neural stem cell (NSC) neuronal differentiation requires a branched chain amino acids-induced persistent metabolic shift towards energy metabolism.
Bifari F, Dolci S, Bottani E, Pino A, Di Chio M, Zorzin S, Ragni M, Zamfir RG, Brunetti D, Bardelli D, Delfino P, Cattaneo MG, Bordo R, Tedesco L, Rossi F, Bossolasco P, Corbo V, Fumagalli G, Nisoli E, Valerio A, Decimo I. Bifari F, et al. Among authors: bottani e. Pharmacol Res. 2020 Aug;158:104863. doi: 10.1016/j.phrs.2020.104863. Epub 2020 May 12. Pharmacol Res. 2020. PMID: 32407957 Free article.
Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells.
Faustini G, Marchesan E, Zonta L, Bono F, Bottani E, Longhena F, Ziviani E, Valerio A, Bellucci A. Faustini G, et al. Among authors: bottani e. Oxid Med Cell Longev. 2019 Nov 23;2019:4246350. doi: 10.1155/2019/4246350. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31871549 Free PMC article.
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak G, Rybak-Wolf A, Lisowski P, Pentimalli TM, Jüttner R, Glažar P, Uppal K, Bottani E, Brunetti D, Secker C, Zink A, Meierhofer D, Henke MT, Dey M, Ciptasari U, Mlody B, Hahn T, Berruezo-Llacuna M, Karaiskos N, Di Virgilio M, Mayr JA, Wortmann SB, Priller J, Gotthardt M, Jones DP, Mayatepek E, Stenzel W, Diecke S, Kühn R, Wanker EE, Rajewsky N, Schuelke M, Prigione A. Inak G, et al. Among authors: bottani e. Nat Commun. 2021 Mar 26;12(1):1929. doi: 10.1038/s41467-021-22117-z. Nat Commun. 2021. PMID: 33771987 Free PMC article.
Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity.
Ciarpella F, Zamfir RG, Campanelli A, Ren E, Pedrotti G, Bottani E, Borioli A, Caron D, Di Chio M, Dolci S, Ahtiainen A, Malpeli G, Malerba G, Bardoni R, Fumagalli G, Hyttinen J, Bifari F, Palazzolo G, Panuccio G, Curia G, Decimo I. Ciarpella F, et al. Among authors: bottani e. iScience. 2021 Nov 15;24(12):103438. doi: 10.1016/j.isci.2021.103438. eCollection 2021 Dec 17. iScience. 2021. PMID: 34901791 Free PMC article.
Therapeutic induction of energy metabolism reduces neural tissue damage and increases microglia activation in severe spinal cord injury.
Dolci S, Mannino L, Bottani E, Campanelli A, Di Chio M, Zorzin S, D'Arrigo G, Amenta A, Segala A, Paglia G, Denti V, Fumagalli G, Nisoli E, Valerio A, Verderio C, Martano G, Bifari F, Decimo I. Dolci S, et al. Among authors: bottani e. Pharmacol Res. 2022 Apr;178:106149. doi: 10.1016/j.phrs.2022.106149. Epub 2022 Feb 28. Pharmacol Res. 2022. PMID: 35240272
36 results