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PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain.
Lu S, Haskali MB, Ruley KM, Dreyfus NJ, DuBois SL, Paul S, Liow JS, Morse CL, Kowalski A, Gladding RL, Gilmore J, Mogg AJ, Morin SM, Lindsay-Scott PJ, Ruble JC, Kant NA, Shcherbinin S, Barth VN, Johnson MP, Cuadrado M, Jambrina E, Mannes AJ, Nuthall HN, Zoghbi SS, Jesudason CD, Innis RB, Pike VW. Lu S, et al. Among authors: kant na. Sci Transl Med. 2020 May 13;12(543):eaau2939. doi: 10.1126/scitranslmed.aau2939. Sci Transl Med. 2020. PMID: 32404505 Free PMC article.
Evaluation of a PET Radioligand to Image O-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse.
Paul S, Haskali MB, Liow JS, Zoghbi SS, Barth VN, Kolodrubetz MC, Bond MR, Morse CL, Gladding RL, Frankland MP, Kant N, Slieker L, Shcherbinin S, Nuthall HN, Zanotti-Fregonara P, Hanover JA, Jesudason C, Pike VW, Innis RB. Paul S, et al. J Nucl Med. 2019 Jan;60(1):129-134. doi: 10.2967/jnumed.118.213231. Epub 2018 Sep 13. J Nucl Med. 2019. PMID: 30213846 Free PMC article.
Evaluation of 11C-LSN3172176 as a Novel PET Tracer for Imaging M1 Muscarinic Acetylcholine Receptors in Nonhuman Primates.
Nabulsi NB, Holden D, Zheng MQ, Bois F, Lin SF, Najafzadeh S, Gao H, Ropchan J, Lara-Jaime T, Labaree D, Shirali A, Slieker L, Jesudason C, Barth V, Navarro A, Kant N, Carson RE, Huang Y. Nabulsi NB, et al. J Nucl Med. 2019 Aug;60(8):1147-1153. doi: 10.2967/jnumed.118.222034. Epub 2019 Feb 7. J Nucl Med. 2019. PMID: 30733324 Free article.