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Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer.
Wei G, An P, Vaid KA, Nasser I, Huang P, Tan L, Zhao S, Schuppan D, Popov YV. Wei G, et al. Among authors: an p. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G174-G188. doi: 10.1152/ajpgi.00041.2019. Epub 2019 Oct 21. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 31630534 Free PMC article.
Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3.
Wei G, Cao J, Huang P, An P, Badlani D, Vaid KA, Zhao S, Wang DQ, Zhuo J, Yin L, Frassetto A, Markel A, Presnyak V, Gandham S, Hua S, Lukacs C, Finn PF, Giangrande PH, Martini PGV, Popov YV. Wei G, et al. Among authors: an p. J Hepatol. 2021 Jun;74(6):1416-1428. doi: 10.1016/j.jhep.2020.12.010. Epub 2020 Dec 17. J Hepatol. 2021. PMID: 33340584 Free PMC article.
KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro.
An P, Zhu JY, Yang Y, Lv P, Tian YH, Chen MK, Luo HS. An P, et al. World J Gastroenterol. 2007 Mar 7;13(9):1445-8. doi: 10.3748/wjg.v13.i9.1445. World J Gastroenterol. 2007. PMID: 17457979 Free PMC article.

RESULTS: KN-93 (5-50 micromol/L) decreased the proliferation of human hepatic stellate cells in a dose-dependent manner from 81.76% (81.76% +/- 2.58% vs 96.63% +/- 2.69%, P < 0.05) to 27.15% (27.15% +/- 2.86% vs 96.59% +/- 2.44%, P < 0.01) after 24 h treatment

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RESULTS: KN-93 (5-50 micromol/L) decreased the proliferation of human hepatic stellate cells in a dose-dependent manner from 81.76% (81.76% …
Prevention of COVID-19 in patients with IBD - Authors' reply.
Ding NS, An P, Dong W, Ding Y. Ding NS, et al. Among authors: an p. Lancet Gastroenterol Hepatol. 2020 Jul;5(7):640-641. doi: 10.1016/S2468-1253(20)30156-4. Lancet Gastroenterol Hepatol. 2020. PMID: 32553142 Free PMC article. No abstract available.
923 results