Pratilas CA - Search Results

1

FLT3-IRAK dual targeting: an exciting new therapeutic option guided by adaptive activation of immune response pathways.

Rabik CA, Wang J, Pratilas CA. Rabik CA, et al. Among authors: pratilas ca. Ann Transl Med. 2020 Apr;8(7):511. doi: 10.21037/atm.2020.01.21. Ann Transl Med. 2020. PMID: 32395555 Free PMC article. No abstract available.

2

Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics.

Taylor Sundby R, Szymanski JJ, Pan A, Jones PA, Mahmood SZ, Reid OH, Srihari D, Armstrong AE, Chamberlain S, Burgic S, Weekley K, Murray B, Patel S, Qaium F, Lucas AN, Fagan M, Dufek A, Meyer CF, Collins NB, Pratilas CA, Dombi E, Gross AM, Kim A, Chrisinger JSA, Dehner CA, Widemann BC, Hirbe AC, Chaudhuri AA, Shern JF. Taylor Sundby R, et al. Among authors: pratilas ca. medRxiv [Preprint]. 2024 Mar 11:2024.01.18.24301053. doi: 10.1101/2024.01.18.24301053. medRxiv. 2024. PMID: 38293154 Free PMC article. Preprint.

3

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAF^V600E-Mutant Brain Tumor.

Wang J, Yao Z, Jonsson P, Allen AN, Qin ACR, Uddin S, Dunkel IJ, Petriccione M, Manova K, Haque S, Rosenblum MK, Pisapia DJ, Rosen N, Taylor BS, Pratilas CA. Wang J, et al. Among authors: pratilas ca. Cancer Discov. 2018 Sep;8(9):1130-1141. doi: 10.1158/2159-8290.CD-17-1263. Epub 2018 Jun 7. Cancer Discov. 2018. PMID: 29880583 Free PMC article.

4

Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition.

Allen A, Qin ACR, Raj N, Wang J, Uddin S, Yao Z, Tang L, Meyers PA, Taylor BS, Berger MF, Yaeger R, Reidy-Lagunes D, Pratilas CA. Allen A, et al. Among authors: pratilas ca. PLoS One. 2019 Jun 3;14(6):e0217399. doi: 10.1371/journal.pone.0217399. eCollection 2019. PLoS One. 2019. PMID: 31158244 Free PMC article.

5

A clinically and genomically annotated nerve sheath tumor biospecimen repository.

Pollard K, Banerjee J, Doan X, Wang J, Guo X, Allaway R, Langmead S, Slobogean B, Meyer CF, Loeb DM, Morris CD, Belzberg AJ, Blakeley JO, Rodriguez FJ, Guinney J, Gosline SJC, Pratilas CA. Pollard K, et al. Among authors: pratilas ca. Sci Data. 2020 Jun 19;7(1):184. doi: 10.1038/s41597-020-0508-5. Sci Data. 2020. PMID: 32561749 Free PMC article.

6

From Genes to -Omics: The Evolving Molecular Landscape of Malignant Peripheral Nerve Sheath Tumor.

Lemberg KM, Wang J, Pratilas CA. Lemberg KM, et al. Among authors: pratilas ca. Genes (Basel). 2020 Jun 24;11(6):691. doi: 10.3390/genes11060691. Genes (Basel). 2020. PMID: 32599735 Free PMC article. Review.

7

Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors.

Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA. Wang J, et al. Among authors: pratilas ca. Cancer Res. 2020 Dec 1;80(23):5367-5379. doi: 10.1158/0008-5472.CAN-20-1365. Epub 2020 Oct 8. Cancer Res. 2020. PMID: 33032988 Free PMC article.

8

Activation of Receptor Tyrosine Kinases Mediates Acquired Resistance to MEK Inhibition in Malignant Peripheral Nerve Sheath Tumors.

Wang J, Pollard K, Calizo A, Pratilas CA. Wang J, et al. Among authors: pratilas ca. Cancer Res. 2021 Feb 1;81(3):747-762. doi: 10.1158/0008-5472.CAN-20-1992. Epub 2020 Nov 17. Cancer Res. 2021. PMID: 33203698 Free PMC article.

9

Combination MEK and mTOR inhibitor therapy is active in models of glioblastoma.

Schreck KC, Allen AN, Wang J, Pratilas CA. Schreck KC, et al. Among authors: pratilas ca. Neurooncol Adv. 2020 Oct 15;2(1):vdaa138. doi: 10.1093/noajnl/vdaa138. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33235998 Free PMC article.

10

Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAF^V600E-Mutant Human Glioma.

Schreck KC, Morin A, Zhao G, Allen AN, Flannery P, Glantz M, Green AL, Jones C, Jones KL, Kilburn LB, Nazemi KJ, Samuel D, Sanford B, Solomon DA, Wang J, Pratilas CA, Nicolaides T, Mulcahy Levy JM. Schreck KC, et al. Among authors: pratilas ca. Clin Cancer Res. 2021 Nov 15;27(22):6197-6208. doi: 10.1158/1078-0432.CCR-21-2660. Epub 2021 Aug 25. Clin Cancer Res. 2021. PMID: 34433654 Free PMC article.

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