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Page 1
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD. Fischer K, et al. Among authors: kleinert m. Nat Commun. 2020 May 8;11(1):2306. doi: 10.1038/s41467-020-16230-8. Nat Commun. 2020. PMID: 32385399 Free PMC article.
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Döring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Köhrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Hofmann SM, Yang B, Tschöp MH, DiMarchi R, Müller TD. Finan B, et al. Among authors: kleinert m. Cell. 2016 Oct 20;167(3):843-857.e14. doi: 10.1016/j.cell.2016.09.014. Epub 2016 Oct 6. Cell. 2016. PMID: 27720451 Free article.
Emerging Poly-Agonists for Obesity and Type 2 Diabetes.
Kleinert M, Clemmensen C, Stemmer K, Müller TD, DiMarchi RD, Tschöp MH. Kleinert M, et al. Obesity (Silver Spring). 2017 Oct;25(10):1647-1649. doi: 10.1002/oby.21932. Obesity (Silver Spring). 2017. PMID: 28948717 No abstract available.
Animal models of obesity and diabetes mellitus.
Kleinert M, Clemmensen C, Hofmann SM, Moore MC, Renner S, Woods SC, Huypens P, Beckers J, de Angelis MH, Schürmann A, Bakhti M, Klingenspor M, Heiman M, Cherrington AD, Ristow M, Lickert H, Wolf E, Havel PJ, Müller TD, Tschöp MH. Kleinert M, et al. Nat Rev Endocrinol. 2018 Mar;14(3):140-162. doi: 10.1038/nrendo.2017.161. Epub 2018 Jan 19. Nat Rev Endocrinol. 2018. PMID: 29348476 Review.
Exercise increases circulating GDF15 in humans.
Kleinert M, Clemmensen C, Sjøberg KA, Carl CS, Jeppesen JF, Wojtaszewski JFP, Kiens B, Richter EA. Kleinert M, et al. Mol Metab. 2018 Mar;9:187-191. doi: 10.1016/j.molmet.2017.12.016. Epub 2018 Jan 17. Mol Metab. 2018. PMID: 29398617 Free PMC article.
Are peptide conjugates the golden therapy against obesity?
Brandt SJ, Kleinert M, Tschöp MH, Müller TD. Brandt SJ, et al. Among authors: kleinert m. J Endocrinol. 2018 Aug;238(2):R109-R119. doi: 10.1530/JOE-18-0264. Epub 2018 May 30. J Endocrinol. 2018. PMID: 29848610 Free PMC article. Review.
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
Dyar KA, Hubert MJ, Mir AA, Ciciliot S, Lutter D, Greulich F, Quagliarini F, Kleinert M, Fischer K, Eichmann TO, Wright LE, Peña Paz MI, Casarin A, Pertegato V, Romanello V, Albiero M, Mazzucco S, Rizzuto R, Salviati L, Biolo G, Blaauw B, Schiaffino S, Uhlenhaut NH. Dyar KA, et al. Among authors: kleinert m. PLoS Biol. 2018 Aug 10;16(8):e2005886. doi: 10.1371/journal.pbio.2005886. eCollection 2018 Aug. PLoS Biol. 2018. PMID: 30096135 Free PMC article.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH. Clemmensen C, et al. Among authors: kleinert m. Nat Commun. 2018 Oct 23;9(1):4304. doi: 10.1038/s41467-018-06769-y. Nat Commun. 2018. PMID: 30353008 Free PMC article.
Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH. Clemmensen C, et al. Among authors: kleinert m. Nat Commun. 2018 Nov 20;9(1):4975. doi: 10.1038/s41467-018-07479-1. Nat Commun. 2018. PMID: 30459311 Free PMC article.
122 results