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The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD. Fischer K, et al. Among authors: collins s. Nat Commun. 2020 May 8;11(1):2306. doi: 10.1038/s41467-020-16230-8. Nat Commun. 2020. PMID: 32385399 Free PMC article.
p62 links β-adrenergic input to mitochondrial function and thermogenesis.
Müller TD, Lee SJ, Jastroch M, Kabra D, Stemmer K, Aichler M, Abplanalp B, Ananthakrishnan G, Bhardwaj N, Collins S, Divanovic S, Endele M, Finan B, Gao Y, Habegger KM, Hembree J, Heppner KM, Hofmann S, Holland J, Küchler D, Kutschke M, Krishna R, Lehti M, Oelkrug R, Ottaway N, Perez-Tilve D, Raver C, Walch AK, Schriever SC, Speakman J, Tseng YH, Diaz-Meco M, Pfluger PT, Moscat J, Tschöp MH. Müller TD, et al. Among authors: collins s. J Clin Invest. 2013 Jan;123(1):469-78. doi: 10.1172/JCI64209. Epub 2012 Dec 21. J Clin Invest. 2013. PMID: 23257354 Free PMC article.
HDAC11 suppresses the thermogenic program of adipose tissue via BRD2.
Bagchi RA, Ferguson BS, Stratton MS, Hu T, Cavasin MA, Sun L, Lin YH, Liu D, Londono P, Song K, Pino MF, Sparks LM, Smith SR, Scherer PE, Collins S, Seto E, McKinsey TA. Bagchi RA, et al. Among authors: collins s. JCI Insight. 2018 Aug 9;3(15):e120159. doi: 10.1172/jci.insight.120159. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089714 Free PMC article.
4,279 results