Dal Peraro M - Search Results

1

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms.

Duarte DP, Lamontanara AJ, La Sala G, Jeong S, Sohn YK, Panjkovich A, Georgeon S, Kükenshöner T, Marcaida MJ, Pojer F, De Vivo M, Svergun D, Kim HS, Dal Peraro M, Hantschel O. Duarte DP, et al. Among authors: dal peraro m. Nat Commun. 2020 May 8;11(1):2319. doi: 10.1038/s41467-020-16128-5. Nat Commun. 2020. PMID: 32385234 Free PMC article.

2

Modeling the charge distribution at metal sites in proteins for molecular dynamics simulations.

Dal Peraro M, Spiegel K, Lamoureux G, De Vivo M, DeGrado WF, Klein ML. Dal Peraro M, et al. J Struct Biol. 2007 Mar;157(3):444-53. doi: 10.1016/j.jsb.2006.10.019. Epub 2006 Oct 27. J Struct Biol. 2007. PMID: 17188512

3

Phosphodiester cleavage in ribonuclease H occurs via an associative two-metal-aided catalytic mechanism.

De Vivo M, Dal Peraro M, Klein ML. De Vivo M, et al. Among authors: dal peraro m. J Am Chem Soc. 2008 Aug 20;130(33):10955-62. doi: 10.1021/ja8005786. Epub 2008 Jul 29. J Am Chem Soc. 2008. PMID: 18662000 Free PMC article.

4

Understanding the effect of magnesium ion concentration on the catalytic activity of ribonuclease H through computation: does a third metal binding site modulate endonuclease catalysis?

Ho MH, De Vivo M, Dal Peraro M, Klein ML. Ho MH, et al. Among authors: dal peraro m. J Am Chem Soc. 2010 Oct 6;132(39):13702-12. doi: 10.1021/ja102933y. J Am Chem Soc. 2010. PMID: 20731347 Free PMC article.

5

Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production.

Dimitrov M, Alattia JR, Lemmin T, Lehal R, Fligier A, Houacine J, Hussain I, Radtke F, Dal Peraro M, Beher D, Fraering PC. Dimitrov M, et al. Among authors: dal peraro m. Nat Commun. 2013;4:2246. doi: 10.1038/ncomms3246. Nat Commun. 2013. PMID: 23907250 Free article.

6

Functional dissection of intersubunit interactions in the EspR virulence regulator of Mycobacterium tuberculosis.

Blasco B, Japaridze A, Stenta M, Wicky BI, Dietler G, Dal Peraro M, Pojer F, Cole ST. Blasco B, et al. Among authors: dal peraro m. J Bacteriol. 2014 May;196(10):1889-900. doi: 10.1128/JB.00039-14. Epub 2014 Mar 14. J Bacteriol. 2014. PMID: 24633871 Free PMC article.

7

Catalytic metal ions and enzymatic processing of DNA and RNA.

Palermo G, Cavalli A, Klein ML, Alfonso-Prieto M, Dal Peraro M, De Vivo M. Palermo G, et al. Among authors: dal peraro m. Acc Chem Res. 2015 Feb 17;48(2):220-8. doi: 10.1021/ar500314j. Epub 2015 Jan 15. Acc Chem Res. 2015. PMID: 25590654 Review.

8

Molecular Simulations Highlight the Role of Metals in Catalysis and Inhibition of Type II Topoisomerase.

Palermo G, Stenta M, Cavalli A, Dal Peraro M, De Vivo M. Palermo G, et al. Among authors: dal peraro m. J Chem Theory Comput. 2013 Feb 12;9(2):857-62. doi: 10.1021/ct300691u. Epub 2013 Jan 9. J Chem Theory Comput. 2013. PMID: 26588728

9

Cooperative motion of a key positively charged residue and metal ions for DNA replication catalyzed by human DNA Polymerase-η.

Genna V, Gaspari R, Dal Peraro M, De Vivo M. Genna V, et al. Among authors: dal peraro m. Nucleic Acids Res. 2016 Apr 7;44(6):2827-36. doi: 10.1093/nar/gkw128. Epub 2016 Mar 1. Nucleic Acids Res. 2016. PMID: 26935581 Free PMC article.

10

A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria.

Murima P, Zimmermann M, Chopra T, Pojer F, Fonti G, Dal Peraro M, Alonso S, Sauer U, Pethe K, McKinney JD. Murima P, et al. Among authors: dal peraro m. Nat Commun. 2016 Aug 24;7:12527. doi: 10.1038/ncomms12527. Nat Commun. 2016. PMID: 27555519 Free PMC article.

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