Kumar AP - Search Results

1

Targeting AKT/mTOR in Oral Cancer: Mechanisms and Advances in Clinical Trials.

Harsha C, Banik K, Ang HL, Girisa S, Vikkurthi R, Parama D, Rana V, Shabnam B, Khatoon E, Kumar AP, Kunnumakkara AB. Harsha C, et al. Among authors: kumar ap. Int J Mol Sci. 2020 May 6;21(9):3285. doi: 10.3390/ijms21093285. Int J Mol Sci. 2020. PMID: 32384682 Free PMC article. Review.

2

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice.

Shanmugam MK, Rajendran P, Li F, Nema T, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Ho PC, Hui KM, Sethi G. Shanmugam MK, et al. Among authors: kumar ap. J Mol Med (Berl). 2011 Jul;89(7):713-27. doi: 10.1007/s00109-011-0746-2. Epub 2011 Apr 5. J Mol Med (Berl). 2011. PMID: 21465181

3

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model.

Shanmugam MK, Manu KA, Ong TH, Ramachandran L, Surana R, Bist P, Lim LH, Kumar AP, Hui KM, Sethi G. Shanmugam MK, et al. Among authors: kumar ap. Int J Cancer. 2011 Oct 1;129(7):1552-63. doi: 10.1002/ijc.26120. Epub 2011 Jul 20. Int J Cancer. 2011. PMID: 21480220 Free article.

4

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways.

Kannaiyan R, Manu KA, Chen L, Li F, Rajendran P, Subramaniam A, Lam P, Kumar AP, Sethi G. Kannaiyan R, et al. Among authors: kumar ap. Apoptosis. 2011 Oct;16(10):1028-41. doi: 10.1007/s10495-011-0629-6. Apoptosis. 2011. PMID: 21786165

5

Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.

Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G. Rajendran P, et al. Among authors: kumar ap. J Cell Physiol. 2012 May;227(5):2184-95. doi: 10.1002/jcp.22954. J Cell Physiol. 2012. PMID: 21792937

6

Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.

Shanmugam MK, Dai X, Kumar AP, Tan BK, Sethi G, Bishayee A. Shanmugam MK, et al. Among authors: kumar ap. Biochem Pharmacol. 2013 Jun 1;85(11):1579-87. doi: 10.1016/j.bcp.2013.03.006. Epub 2013 Mar 13. Biochem Pharmacol. 2013. PMID: 23499879 Free article.

7

Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model.

Siveen KS, Ahn KS, Ong TH, Shanmugam MK, Li F, Yap WN, Kumar AP, Fong CW, Tergaonkar V, Hui KM, Sethi G. Siveen KS, et al. Among authors: kumar ap. Oncotarget. 2014 Apr 15;5(7):1897-911. doi: 10.18632/oncotarget.1876. Oncotarget. 2014. PMID: 24722367 Free PMC article.

8

NF-κB in cancer therapy.

Li F, Zhang J, Arfuso F, Chinnathambi A, Zayed ME, Alharbi SA, Kumar AP, Ahn KS, Sethi G. Li F, et al. Among authors: kumar ap. Arch Toxicol. 2015 May;89(5):711-31. doi: 10.1007/s00204-015-1470-4. Epub 2015 Feb 18. Arch Toxicol. 2015. PMID: 25690730 Review.

9

Targeting transcription factor STAT3 for cancer prevention and therapy.

Chai EZ, Shanmugam MK, Arfuso F, Dharmarajan A, Wang C, Kumar AP, Samy RP, Lim LH, Wang L, Goh BC, Ahn KS, Hui KM, Sethi G. Chai EZ, et al. Among authors: kumar ap. Pharmacol Ther. 2016 Jun;162:86-97. doi: 10.1016/j.pharmthera.2015.10.004. Epub 2016 Feb 12. Pharmacol Ther. 2016. PMID: 26478441 Review.

10

The potential role of boswellic acids in cancer prevention and treatment.

Roy NK, Deka A, Bordoloi D, Mishra S, Kumar AP, Sethi G, Kunnumakkara AB. Roy NK, et al. Among authors: kumar ap. Cancer Lett. 2016 Jul 10;377(1):74-86. doi: 10.1016/j.canlet.2016.04.017. Epub 2016 Apr 14. Cancer Lett. 2016. PMID: 27091399 Review.

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