Wynn JL - Search Results

1

BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.

Brook B, Harbeson DJ, Shannon CP, Cai B, He D, Ben-Othman R, Francis F, Huang J, Varankovich N, Liu A, Bao W, Bjerregaard-Andersen M, Schaltz-Buchholzer F, Sanca L, Golding CN, Larsen KL, Levy O, Kampmann B; EPIC Consortium; Tan R, Charles A, Wynn JL, Shann F, Aaby P, Benn CS, Tebbutt SJ, Kollmann TR, Amenyogbe N. Brook B, et al. Among authors: wynn jl. Sci Transl Med. 2020 May 6;12(542):eaax4517. doi: 10.1126/scitranslmed.aax4517. Sci Transl Med. 2020. PMID: 32376769 Free PMC article.

2

Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists.

Wynn JL, Scumpia PO, Winfield RD, Delano MJ, Kelly-Scumpia K, Barker T, Ungaro R, Levy O, Moldawer LL. Wynn JL, et al. Blood. 2008 Sep 1;112(5):1750-8. doi: 10.1182/blood-2008-01-130500. Epub 2008 Jun 30. Blood. 2008. PMID: 18591384 Free PMC article.

3

Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis.

Wynn JL, Neu J, Moldawer LL, Levy O. Wynn JL, et al. J Perinatol. 2009 Feb;29(2):79-88. doi: 10.1038/jp.2008.132. Epub 2008 Sep 4. J Perinatol. 2009. PMID: 18769381 Free PMC article. Review.

4

Role of innate host defenses in susceptibility to early-onset neonatal sepsis.

Wynn JL, Levy O. Wynn JL, et al. Clin Perinatol. 2010 Jun;37(2):307-37. doi: 10.1016/j.clp.2010.04.001. Clin Perinatol. 2010. PMID: 20569810 Free PMC article. Review.

5

Role of innate immunity in neonatal infection.

Cuenca AG, Wynn JL, Moldawer LL, Levy O. Cuenca AG, et al. Among authors: wynn jl. Am J Perinatol. 2013 Feb;30(2):105-12. doi: 10.1055/s-0032-1333412. Epub 2013 Jan 7. Am J Perinatol. 2013. PMID: 23297181 Free PMC article. Review.

6

A prime time for trained immunity: innate immune memory in newborns and infants.

Levy O, Wynn JL. Levy O, et al. Among authors: wynn jl. Neonatology. 2014;105(2):136-41. doi: 10.1159/000356035. Epub 2013 Dec 18. Neonatology. 2014. PMID: 24356292 Free PMC article. Review.

7

Early onset and hospital acquired neonatal sepsis associated with high mortality.

Wynn JL. Wynn JL. J Pediatr. 2019 Jan;204:320-323. doi: 10.1016/j.jpeds.2018.10.075. J Pediatr. 2019. PMID: 30579470 No abstract available.

8

Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis.

Wynn JL, Scumpia PO, Delano MJ, O'Malley KA, Ungaro R, Abouhamze A, Moldawer LL. Wynn JL, et al. Shock. 2007 Dec;28(6):675-683. doi: 10.1097/SHK.0b013e3180556d09. Shock. 2007. PMID: 17621256

9

Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10.

Kelly-Scumpia KM, Scumpia PO, Delano MJ, Weinstein JS, Cuenca AG, Wynn JL, Moldawer LL. Kelly-Scumpia KM, et al. Among authors: wynn jl. J Exp Med. 2010 Feb 15;207(2):319-26. doi: 10.1084/jem.20091959. Epub 2010 Jan 13. J Exp Med. 2010. PMID: 20071504 Free PMC article.

10

B cells enhance early innate immune responses during bacterial sepsis.

Kelly-Scumpia KM, Scumpia PO, Weinstein JS, Delano MJ, Cuenca AG, Nacionales DC, Wynn JL, Lee PY, Kumagai Y, Efron PA, Akira S, Wasserfall C, Atkinson MA, Moldawer LL. Kelly-Scumpia KM, et al. Among authors: wynn jl. J Exp Med. 2011 Aug 1;208(8):1673-82. doi: 10.1084/jem.20101715. Epub 2011 Jul 11. J Exp Med. 2011. PMID: 21746813 Free PMC article.

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