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Page 1
iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation.
Fleischer A, Vallejo-Díez S, Martín-Fernández JM, Sánchez-Gilabert A, Castresana M, Del Pozo A, Esquisabel A, Ávila S, Castrillo JL, Gaínza E, Pedraz JL, Viñas M, Bachiller D. Fleischer A, et al. Among authors: martin fernandez jm. Mol Ther Methods Clin Dev. 2020 Apr 18;17:858-870. doi: 10.1016/j.omtm.2020.04.005. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32373648 Free PMC article.
Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene.
Vallejo-Diez S, Fleischer A, Martín-Fernández JM, Sánchez-Gilabert A, Castresana M, Aguillón D, Villegas A, Mastronardi CA, Espinosa LG, Arcos-Burgos M, Del Pozo Á, Herrán E, Gainza E, Isaza-Ruget M, Lopera F, Bachiller D. Vallejo-Diez S, et al. Among authors: martin fernandez jm. Stem Cell Res. 2019 May;37:101440. doi: 10.1016/j.scr.2019.101440. Epub 2019 Apr 15. Stem Cell Res. 2019. PMID: 31026686 Free article.
New Bicistronic TALENs Greatly Improve Genome Editing.
Martín-Fernández JM, Fleischer A, Vallejo-Diez S, Palomino E, Sánchez-Gilabert A, Ruiz R, Bejarano Y, Llinàs P, Gayá A, Bachiller D. Martín-Fernández JM, et al. Curr Protoc Stem Cell Biol. 2020 Mar;52(1):e104. doi: 10.1002/cpsc.104. Curr Protoc Stem Cell Biol. 2020. PMID: 32023363
The role of the different CD3γ domains in TCR expression and signaling.
Garcillán B, Megino RF, Herrero-Alonso M, Guardo AC, Perez-Flores V, Juraske C, Idstein V, Martin-Fernandez JM, Geisler C, Schamel WWA, Marin AV, Regueiro JR. Garcillán B, et al. Among authors: martin fernandez jm. Front Immunol. 2022 Sep 2;13:978658. doi: 10.3389/fimmu.2022.978658. eCollection 2022. Front Immunol. 2022. PMID: 36119034 Free PMC article.
Toward gene therapy for human CD3 deficiencies.
Pacheco-Castro A, Martín-Fernández JM, Millán R, Sanal O, Allende L, Regueiro JR. Pacheco-Castro A, et al. Among authors: martin fernandez jm. Hum Gene Ther. 2003 Nov 20;14(17):1653-61. doi: 10.1089/104303403322542293. Hum Gene Ther. 2003. PMID: 14633407
TCR dynamics in human mature T lymphocytes lacking CD3 gamma.
Torres PS, Alcover A, Zapata DA, Arnaud J, Pacheco A, Martín-Fernández JM, Villasevil EM, Sanal O, Regueiro JR. Torres PS, et al. Among authors: martin fernandez jm. J Immunol. 2003 Jun 15;170(12):5947-55. doi: 10.4049/jimmunol.170.12.5947. J Immunol. 2003. PMID: 12794121