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Tryptophan catabolism reflects disease activity in human tuberculosis.
Collins JM, Siddiqa A, Jones DP, Liu K, Kempker RR, Nizam A, Shah NS, Ismail N, Ouma SG, Tukvadze N, Li S, Day CL, Rengarajan J, Brust JC, Gandhi NR, Ernst JD, Blumberg HM, Ziegler TR. Collins JM, et al. Among authors: rengarajan j. JCI Insight. 2020 May 21;5(10):e137131. doi: 10.1172/jci.insight.137131. JCI Insight. 2020. PMID: 32369456 Free PMC article. Clinical Trial.
In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.
Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, Rengarajan J, Khader SA, Kaushal D, Mehra S. Gautam US, et al. Among authors: rengarajan j. Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E62-E71. doi: 10.1073/pnas.1711373114. Epub 2017 Dec 18. Proc Natl Acad Sci U S A. 2018. PMID: 29255022 Free PMC article.
A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection.
Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, Ouma GS, Ouma SG, Beck AA, Mulligan MJ, Oladele A, Kaushal D, Cain KP, Waller L, Blumberg HM, Altman JD, Ernst JD, Rengarajan J, Day CL; TBRU-ASTRa Study Group. Whatney WE, et al. Among authors: rengarajan j. J Immunol. 2018 Apr 15;200(8):3008-3019. doi: 10.4049/jimmunol.1701737. Epub 2018 Mar 14. J Immunol. 2018. PMID: 29540577 Free PMC article.
Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques.
Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Foreman TW, et al. Among authors: rengarajan j. Am J Respir Crit Care Med. 2020 Feb 15;201(4):469-477. doi: 10.1164/rccm.201903-0646OC. Am J Respir Crit Care Med. 2020. PMID: 31647877 Free PMC article. Retracted.
Schistosoma mansoni Infection Is Associated With a Higher Probability of Tuberculosis Disease in HIV-Infected Adults in Kenya.
McLaughlin TA, Nizam A, Hayara FO, Ouma GS, Campbell A, Khayumbi J, Ongalo J, Ouma SG, Shah NS, Altman JD, Kaushal D, Rengarajan J, Ernst JD, Blumberg HM, Waller LA, Gandhi NR, Day CL, Benkeser D. McLaughlin TA, et al. Among authors: rengarajan j. J Acquir Immune Defic Syndr. 2021 Feb 1;86(2):157-163. doi: 10.1097/QAI.0000000000002536. J Acquir Immune Defic Syndr. 2021. PMID: 33074856 Free PMC article.
51 results