Ishizaka T - Search Results

1

Comprehensive analysis of cardiac function, blood biomarkers and histopathology for milrinone-induced cardiotoxicity in cynomolgus monkeys.

Chiba K, Ishizaka T, Yoshimatsu Y, Mikamoto K, Maeda Y, Iguchi T, Shirai M, Yamaguchi T, Goto K, Sakurai K, Tamai S, Kataoka H, Hasegawa M, Mori K. Chiba K, et al. Among authors: ishizaka t. J Pharmacol Toxicol Methods. 2020 May-Jun;103:106870. doi: 10.1016/j.vascn.2020.106870. Epub 2020 Apr 28. J Pharmacol Toxicol Methods. 2020. PMID: 32353509

2

Evaluation of drug-induced QT prolongation in a halothane-anesthetized monkey model: effects of sotalol.

Ishizaka T, Yoshimatsu Y, Ozawa M, Kimotsuki T, Takasaki W, Manabe S, Yasuda M. Ishizaka T, et al. J Pharmacol Toxicol Methods. 2009 Mar-Apr;59(2):86-93. doi: 10.1016/j.vascn.2009.01.002. J Pharmacol Toxicol Methods. 2009. PMID: 19367688

3

Age-related differences of QT interval and autonomic nervous system activity in female cynomolgus monkeys.

Ishizaka T, Yoshimatsu Y, Ozawa M, Kimotsuki T, Takasaki W, Manabe S, Yasuda M. Ishizaka T, et al. J Pharmacol Toxicol Methods. 2009 Nov-Dec;60(3):288-95. doi: 10.1016/j.vascn.2009.06.003. Epub 2009 Jul 6. J Pharmacol Toxicol Methods. 2009. PMID: 19586616

4

Promising approach for the preclinical assessment of cardiac risks using left ventricular pressure-volume loop analyses in anesthetized monkeys.

Ishizaka T, Yoshimatsu Y, Maeda Y, Takasaki W, Chiba K, Mori K. Ishizaka T, et al. J Pharmacol Toxicol Methods. 2017 Mar-Apr;84:1-10. doi: 10.1016/j.vascn.2016.10.004. Epub 2016 Oct 15. J Pharmacol Toxicol Methods. 2017. PMID: 27756610

5

Usefulness of simultaneous and sequential monitoring of glucose level and electrocardiogram in monkeys treated with gatifloxacin under conscious and nonrestricted conditions.

Yoshimatsu Y, Ishizaka T, Chiba K, Mori K. Yoshimatsu Y, et al. Among authors: ishizaka t. Exp Anim. 2018 May 10;67(2):281-290. doi: 10.1538/expanim.17-0136. Epub 2018 Jan 3. Exp Anim. 2018. PMID: 29311442 Free PMC article.

6

Inotropic Effects of Nicorandil on Cardiac Contractility Assessed by Left Ventricular Pressure-Volume Relationship Analyses in Anesthetized Monkeys.

Ishizaka T, Yoshimatsu Y, Maeda Y, Chiba K, Mori K. Ishizaka T, et al. J Cardiovasc Pharmacol. 2018 Feb;71(2):76-81. doi: 10.1097/FJC.0000000000000548. J Cardiovasc Pharmacol. 2018. PMID: 29420355

7

Negative lusitropic property of nifekalant identified using ventricular pressure-volume loop analyses in anesthetized monkeys.

Ishizaka T, Yoshimatsu Y, Maeda Y, Chiba K, Mori K. Ishizaka T, et al. Exp Anim. 2019 Feb 26;68(1):91-102. doi: 10.1538/expanim.18-0098. Epub 2018 Oct 17. Exp Anim. 2019. PMID: 30333366 Free PMC article.

8

Exposure-response analysis of drug-induced QT interval prolongation in telemetered monkeys for translational prediction to human.

Komatsu R, Mizuno H, Ishizaka T, Ito A, Jikuzono T, Kakoi T, Bando M, Koga T, Handa J, Takahashi Y, Kanno A, Ozaki H, Chiba K; Japan activity for Improvement of Cardiovascular Evaluation by Telemetry system (J-ICET). Komatsu R, et al. Among authors: ishizaka t. J Pharmacol Toxicol Methods. 2019 Sep-Oct;99:106606. doi: 10.1016/j.vascn.2019.106606. Epub 2019 Jun 27. J Pharmacol Toxicol Methods. 2019. PMID: 31255745

9

A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization.

Hashimoto Y, Koyama K, Kamai Y, Hirotani K, Ogitani Y, Zembutsu A, Abe M, Kaneda Y, Maeda N, Shiose Y, Iguchi T, Ishizaka T, Karibe T, Hayakawa I, Morita K, Nakada T, Nomura T, Wakita K, Kagari T, Abe Y, Murakami M, Ueno S, Agatsuma T. Hashimoto Y, et al. Among authors: ishizaka t. Clin Cancer Res. 2019 Dec 1;25(23):7151-7161. doi: 10.1158/1078-0432.CCR-19-1745. Epub 2019 Aug 30. Clin Cancer Res. 2019. PMID: 31471314

10

Ultrasonographic measurement of the renal resistive index in the cynomolgus monkey (Macaca fascicularis) under conscious and ketamine-immobilized conditions.

Konno H, Ishizaka T, Chiba K, Mori K. Konno H, et al. Among authors: ishizaka t. Exp Anim. 2020 Jan 29;69(1):119-126. doi: 10.1538/expanim.19-0084. Epub 2019 Oct 22. Exp Anim. 2020. PMID: 31645524 Free PMC article.

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