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Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Oncogene. 2020 May;39(22):4465-4474. doi: 10.1038/s41388-020-1304-6. Epub 2020 Apr 29.
Oncogene. 2020.
PMID: 32350444
Free PMC article.
Dual inhibitors of LSD1 and spermine oxidase.
Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA Jr, Woster PM.
Holshouser S, et al.
Medchemcomm. 2019 Feb 8;10(5):778-790. doi: 10.1039/c8md00610e. eCollection 2019 May 1.
Medchemcomm. 2019.
PMID: 31191868
Free PMC article.
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Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease.
Holshouser S, Cafiero R, Robinson M, Kirkpatrick J, Casero RA Jr, Hyacinth HI, Woster PM.
Holshouser S, et al.
ACS Omega. 2020 Jun 9;5(24):14750-14758. doi: 10.1021/acsomega.0c01585. eCollection 2020 Jun 23.
ACS Omega. 2020.
PMID: 32596612
Free PMC article.
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3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors.
Kutz CJ, Holshouser SL, Marrow EA, Woster PM.
Kutz CJ, et al. Among authors: holshouser sl.
Medchemcomm. 2014 Dec;5(12):1863-1870. doi: 10.1039/C4MD00283K.
Medchemcomm. 2014.
PMID: 25580204
Free PMC article.
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Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.
Nowotarski SL, Pachaiyappan B, Holshouser SL, Kutz CJ, Li Y, Huang Y, Sharma SK, Casero RA Jr, Woster PM.
Nowotarski SL, et al. Among authors: holshouser sl.
Bioorg Med Chem. 2015 Apr 1;23(7):1601-12. doi: 10.1016/j.bmc.2015.01.049. Epub 2015 Feb 7.
Bioorg Med Chem. 2015.
PMID: 25725609
Free PMC article.
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Corrigendum to "Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures" [Bioorg. Med. Chem. 23 (2015) 1601-1612].
Nowotarski SL, Pachaiyappan B, Holshouser SL, Kutz CJ, Li Y, Huang Y, Sharma SK, Casero RA Jr, Woster PM.
Nowotarski SL, et al. Among authors: holshouser sl.
Bioorg Med Chem. 2018 Jul 23;26(12):3728-3729. doi: 10.1016/j.bmc.2018.05.032. Epub 2018 May 30.
Bioorg Med Chem. 2018.
PMID: 29859749
No abstract available.
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Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen.
Temkin AM, Bowers RR, Magaletta ME, Holshouser S, Maggi A, Ciana P, Guillette LJ, Bowden JA, Kucklick JR, Baatz JE, Spyropoulos DD.
Temkin AM, et al.
Environ Health Perspect. 2016 Jan;124(1):112-9. doi: 10.1289/ehp.1409672. Epub 2015 Jul 2.
Environ Health Perspect. 2016.
PMID: 26135921
Free PMC article.
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