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Production of the Cytotoxic Cardenolide Glucoevatromonoside by Semisynthesis and Biotransformation of Evatromonoside by a Digitalis lanata Cell Culture.
Munkert J, Santiago Franco M, Nolte E, Thaís Silva I, Oliveira Castilho R, Melo Ottoni F, Schneider NFZ, Oliveira MC, Taubert H, Bauer W, Andrade SF, Alves RJ, Simões CMO, Braga FC, Kreis W, de Pádua RM. Munkert J, et al. Among authors: de padua rm. Planta Med. 2017 Aug;83(12-13):1035-1043. doi: 10.1055/s-0043-109557. Epub 2017 May 9. Planta Med. 2017. PMID: 28486743
Forced degradation of l-(+)-bornesitol, a bioactive marker of Hancornia speciosa: Development and validation of stability indicating UHPLC-MS method and effect of degraded products on ACE inhibition.
Gomes JHS, da Silva GC, Côrtes SF, de Pádua RM, Braga FC. Gomes JHS, et al. Among authors: de padua rm. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Sep 1;1093-1094:31-38. doi: 10.1016/j.jchromb.2018.06.045. Epub 2018 Jun 22. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29980101
Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
Silva IT, Munkert J, Nolte E, Schneider NFZ, Rocha SC, Ramos ACP, Kreis W, Braga FC, de Pádua RM, Taranto AG, Cortes V, Barbosa LA, Wach S, Taubert H, Simões CMO. Silva IT, et al. Among authors: de padua rm. Biomed Pharmacother. 2018 Nov;107:464-474. doi: 10.1016/j.biopha.2018.08.028. Epub 2018 Aug 11. Biomed Pharmacother. 2018. PMID: 30107342
Exploring the bioactivity potential of Leonotis nepetifolia: phytochemical composition, antimicrobial and antileishmanial activities of extracts from different anatomical parts.
de Oliveira DP, de Almeida L, Marques MJ, de Carvalho RR, Dias ALT, da Silva GA, de Pádua RM, Braga FC, da Silva MA. de Oliveira DP, et al. Among authors: de padua rm. Nat Prod Res. 2021 Sep;35(18):3120-3125. doi: 10.1080/14786419.2019.1686367. Epub 2019 Nov 6. Nat Prod Res. 2021. PMID: 31691582
Determination of l-(+)-bornesitol, the hypotensive constituent of Hancornia speciosa, in rat plasma by LC-MS/MS and its application on a pharmacokinetic study.
Moreira LN, Feltrin C, Gonçalves JE, de Castro WV, Simões CMO, de Pádua RM, Cortes SF, Braga FC. Moreira LN, et al. Among authors: de padua rm. Biomed Pharmacother. 2020 Dec;132:110900. doi: 10.1016/j.biopha.2020.110900. Epub 2020 Oct 28. Biomed Pharmacother. 2020. PMID: 33113433 Free article.
Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na+,K+-ATPase and ion channels on lung cancer cells.
Schneider NFZ, Menegaz D, Dagostin ALA, Persich L, Rocha SC, Ramos ACP, Cortes VF, Fontes CFL, de Pádua RM, Munkert J, Kreis W, Braga FC, Barbosa LA, Silva FRMB, Simões CMO. Schneider NFZ, et al. Among authors: de padua rm. Mol Cell Biochem. 2021 Apr;476(4):1825-1848. doi: 10.1007/s11010-020-04040-x. Epub 2021 Jan 18. Mol Cell Biochem. 2021. PMID: 33459980
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