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Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease.
Govender L, Abel B, Hughes EJ, Scriba TJ, Kagina BM, de Kock M, Walzl G, Black G, Rosenkrands I, Hussey GD, Mahomed H, Andersen P, Hanekom WA. Govender L, et al. Among authors: scriba tj. Vaccine. 2010 Dec 10;29(1):51-7. doi: 10.1016/j.vaccine.2010.10.022. Epub 2010 Oct 23. Vaccine. 2010. PMID: 20974305 Free PMC article.
Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis.
Rozot V, Patrizia A, Vigano S, Mazza-Stalder J, Idrizi E, Day CL, Perreau M, Lazor-Blanchet C, Ohmiti K, Goletti D, Bart PA, Hanekom W, Scriba TJ, Nicod L, Pantaleo G, Harari A. Rozot V, et al. Among authors: scriba tj. Clin Infect Dis. 2015 Feb 1;60(3):432-7. doi: 10.1093/cid/ciu795. Epub 2014 Oct 31. Clin Infect Dis. 2015. PMID: 25362202 Free PMC article.
COMPASS identifies T-cell subsets correlated with clinical outcomes.
Lin L, Finak G, Ushey K, Seshadri C, Hawn TR, Frahm N, Scriba TJ, Mahomed H, Hanekom W, Bart PA, Pantaleo G, Tomaras GD, Rerks-Ngarm S, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Michael NL, Kim JH, Robb ML, O'Connell RJ, Karasavvas N, Gilbert P, C De Rosa S, McElrath MJ, Gottardo R. Lin L, et al. Among authors: scriba tj. Nat Biotechnol. 2015 Jun;33(6):610-6. doi: 10.1038/nbt.3187. Epub 2015 May 25. Nat Biotechnol. 2015. PMID: 26006008 Free PMC article. Clinical Trial.
A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents.
Carpenter C, Sidney J, Kolla R, Nayak K, Tomiyama H, Tomiyama C, Padilla OA, Rozot V, Ahamed SF, Ponte C, Rolla V, Antas PR, Chandele A, Kenneth J, Laxmi S, Makgotlho E, Vanini V, Ippolito G, Kazanova AS, Panteleev AV, Hanekom W, Mayanja-Kizza H, Lewinsohn D, Saito M, McElrath MJ, Boom WH, Goletti D, Gilman R, Lyadova IV, Scriba TJ, Kallas EG, Murali-Krishna K, Sette A, Lindestam Arlehamn CS. Carpenter C, et al. Among authors: scriba tj. Tuberculosis (Edinb). 2015 Dec;95(6):713-721. doi: 10.1016/j.tube.2015.07.001. Epub 2015 Aug 1. Tuberculosis (Edinb). 2015. PMID: 26277695 Free PMC article.
The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans.
Mothé BR, Lindestam Arlehamn CS, Dow C, Dillon MBC, Wiseman RW, Bohn P, Karl J, Golden NA, Gilpin T, Foreman TW, Rodgers MA, Mehra S, Scriba TJ, Flynn JL, Kaushal D, O'Connor DH, Sette A. Mothé BR, et al. Among authors: scriba tj. Tuberculosis (Edinb). 2015 Dec;95(6):722-735. doi: 10.1016/j.tube.2015.07.005. Epub 2015 Aug 28. Tuberculosis (Edinb). 2015. PMID: 26526557 Free PMC article.
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Fletcher HA, Snowden MA, Landry B, Rida W, Satti I, Harris SA, Matsumiya M, Tanner R, O'Shea MK, Dheenadhayalan V, Bogardus L, Stockdale L, Marsay L, Chomka A, Harrington-Kandt R, Manjaly-Thomas ZR, Naranbhai V, Stylianou E, Darboe F, Penn-Nicholson A, Nemes E, Hatherill M, Hussey G, Mahomed H, Tameris M, McClain JB, Evans TG, Hanekom WA, Scriba TJ, McShane H. Fletcher HA, et al. Among authors: scriba tj. Nat Commun. 2016 Apr 12;7:11290. doi: 10.1038/ncomms11290. Nat Commun. 2016. PMID: 27068708 Free PMC article. Clinical Trial.
259 results