Krimm I - Search Results

1

Miniaturized weak affinity chromatography for ligand identification of nanodiscs-embedded G-protein coupled receptors.

Lecas L, Hartmann L, Caro L, Mohamed-Bouteben S, Raingeval C, Krimm I, Wagner R, Dugas V, Demesmay C. Lecas L, et al. Among authors: krimm i. Anal Chim Acta. 2020 May 29;1113:26-35. doi: 10.1016/j.aca.2020.03.062. Epub 2020 Apr 3. Anal Chim Acta. 2020. PMID: 32340666

2

Ligand specificity, privileged substructures and protein druggability from fragment-based screening.

Barelier S, Krimm I. Barelier S, et al. Among authors: krimm i. Curr Opin Chem Biol. 2011 Aug;15(4):469-74. doi: 10.1016/j.cbpa.2011.02.020. Epub 2011 Mar 14. Curr Opin Chem Biol. 2011. PMID: 21411360 Review.

3

NMR-based analysis of protein-ligand interactions.

Cala O, Guillière F, Krimm I. Cala O, et al. Among authors: krimm i. Anal Bioanal Chem. 2014 Feb;406(4):943-56. doi: 10.1007/s00216-013-6931-0. Epub 2013 Apr 18. Anal Bioanal Chem. 2014. PMID: 23591643 Review.

4

Overview of Probing Protein-Ligand Interactions Using NMR.

Aguirre C, Cala O, Krimm I. Aguirre C, et al. Among authors: krimm i. Curr Protoc Protein Sci. 2015 Aug 3;81:17.18.1-17.18.24. doi: 10.1002/0471140864.ps1718s81. Curr Protoc Protein Sci. 2015. PMID: 26237672 Review.

5

Ligand-Orientation Based Fragment Selection in STD NMR Screening.

Cala O, Krimm I. Cala O, et al. Among authors: krimm i. J Med Chem. 2015 Nov 12;58(21):8739-42. doi: 10.1021/acs.jmedchem.5b01114. Epub 2015 Oct 29. J Med Chem. 2015. PMID: 26492576

6

Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor.

Igonet S, Raingeval C, Cecon E, Pučić-Baković M, Lauc G, Cala O, Baranowski M, Perez J, Jockers R, Krimm I, Jawhari A. Igonet S, et al. Among authors: krimm i. Sci Rep. 2018 May 25;8(1):8142. doi: 10.1038/s41598-018-26113-0. Sci Rep. 2018. PMID: 29802269 Free PMC article.

7

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery.

Raingeval C, Cala O, Brion B, Le Borgne M, Hubbard RE, Krimm I. Raingeval C, et al. Among authors: krimm i. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1218-1225. doi: 10.1080/14756366.2019.1636235. J Enzyme Inhib Med Chem. 2019. PMID: 31286785 Free PMC article.

8

NMR investigation of protein-ligand interactions for G-protein coupled receptors.

Raingeval C, Krimm I. Raingeval C, et al. Among authors: krimm i. Future Med Chem. 2019 Jul;11(14):1811-1825. doi: 10.4155/fmc-2018-0312. Epub 2019 Jul 9. Future Med Chem. 2019. PMID: 31287732 Review.

9

Fragment Linking Strategies for Structure-Based Drug Design.

Bancet A, Raingeval C, Lomberget T, Le Borgne M, Guichou JF, Krimm I. Bancet A, et al. Among authors: krimm i. J Med Chem. 2020 Oct 22;63(20):11420-11435. doi: 10.1021/acs.jmedchem.0c00242. Epub 2020 Jun 23. J Med Chem. 2020. PMID: 32539387 Review.

10

Preparation of miniaturized hydrophilic affinity monoliths: Towards a reduction of non-specific interactions and an increased target protein density.

Gil J, Krimm I, Dugas V, Demesmay C. Gil J, et al. Among authors: krimm i. J Chromatogr A. 2023 Jan 4;1687:463670. doi: 10.1016/j.chroma.2022.463670. Epub 2022 Nov 24. J Chromatogr A. 2023. PMID: 36463648 Free article.

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